Selective reduction of multifetal pregnancy using high intensity focud ultrasound in the rabbit
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期刊名称： Ultrasound in Obstetrics & Gynecology
查询网站ip作者： Bettina Paek,Jessica Foley,V Zderic,Frank Starr,Shahram Vaezy
风雨造句年份： 2005年
期号： 第3期
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牛一定律关键词： fetal therapy;fetus;HIFU;non‐invasive;lective reduction;tissue ablation成语故事亡羊补牢
人物速写简单摘要：Objective High-order multifetal pregnancies carry a significant risk of obstetric complications and poor pregnancy outcome. Selective reduction has traditionally been performed using transabdominal and transvaginal ultrasound-guided intracardiac injection of potassium chloride. We have previously shown that high-intensity focud ultrasound (HIFU) can create a coagulative tissue necrosis in the sh
eep fetus. The objective of this study was to investigate the feasibility of non-invasive lective fetal reduction using HIFU in a rabbit model. Methods A protocol for HIFU-induced tissue coagulation was developed in the rabbit model. The fetal heart was targeted with ultrasound-guided tissue ablation by a HIFU beam. Five time-mated does between 20–29 days' gestation underwent transabdominal fetal cardiac ablation in a total of
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