1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DIESTER

更新时间:2023-06-15 03:51:44 阅读: 评论:0

柳公权的书法作品专利名称:1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DIESTER DERIVATIVE, ITS
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PREPARATION AND DRUG CONTAINING
SAID DERIVATIVE AS ACTIVE COMPONENT 发明人:YAMAGUCHI HISAO,SUGANO
空的多音字HIDEO,OKAMIYA YOSHIAKI,SUNAKAWA
KIYOTAKA
申请号:JP9699583
申请日:19830602
公开号:JPS59222474A
友谊的名句公开日:
全球环境污染现状19841214
专利内容由知识产权出版社提供
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摘要:NEW MATERIAL:The compound of formula I (R<1> and R<3> are lower alkyl;
R<2> are substituted or unsubstituted benzyl, or substituted or unsubstituted phenetyl;
风水命理A is 1-6C straight or branched alkylene; X and Y are halogen or NO2) or its acid addition salt. EXAMPLE:2,6-Dimethyl-4-( 2',3'-dichlorophenyl )-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl ester 5-[2-N-benzyl-N-methylamino)-ethyl] ester. USE:A long-acting drug having excellent pharmacological activities such as hypotensive action, vasodilating action, etc., and uful as a drug for the circulatory dias such as stenocardia, cerebral blood flow and circulatory disorder, hypertension, ischemic cardiopathy, etc. PREPARATION:The compound of formula I can be prepared by reacting the compound of formula II with the compound of formula III and the compound of formula IV. If necessary, the product is subjected to the salt-forming reaction.
申请人:TEIJIN KK
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