专利名称：Inter-phenylene CBA compounds 发明人：Norman A. Nelson糖醋藕片的做法家常
爱心的图片可爱>dnf角色查询申请号：US06/219131
核舟记图片申请日：19801222
公开号：US04306076A
公开日：
19811215
专利内容由知识产权出版社提供
静夜思教案摘要：The prent specification provides novel analogs of carbacyclin (CBA. sub.2), 6a-carba-prostacyclin (6a-carba-PGI.sub.2), which have pronounced prostacyclin-like pharmacological activity, e.g., as platelet anti- aggregatory agents. Specifically the novel chemical analogs of CBA.sub.2 are tho substituted by fluoro (C-5), alkyl (C-9), interphenylene (C-5), and methano (C-6a,9). Further provided are benzindene analogs of CBA.sub. 2 and substituted forms thereof, i.e., 9- deoxy-2',9-methano (or 2',9- metheno)-3-oxa-4,5,6-trinor-3,7-(1',3'- interphenylene)-PGF.sub.1 compounds. Also provided are a variety of novel chemical intermediates, e. g., substituted bicyclo[3.3.0]octane intermediates, and chemical process utilizing such intermediates which are uful in the preparation of the novel CBA.sub.2 analogs.
申请人：THE UPJOHN COMPANY扎达县>烤箱烤鸡腿
代理人：L. Ruth Hattan,Robert A. Armitage
更多信息请下载全文后查看卢钦
