专利名称：Derivatives of perhydro-aza-heterocycles 发明人：Romeo Paioni
申请号：US05/827274
国庆内容申请日：19770824
辣子炒肉
公开号：US04160837A
公开日：
吉林景点19790710
专利内容由知识产权出版社提供数字新媒体
摘要：The prent invention provides new derivatives of perhydro-aza- heterocycles of the formula ##STR1## in which X is the oxo radical or hydrogen and the radical
跳绳瘦胸吗OR.sub.1, in which R.sub.1 is hydrogen or a substituted or unsubstituted aliphatic hydrocarbon radical, a substituted or unsubstituted araliphatic hydrocarbon radical or a substituted or unsubstituted aromatic hydrocarbon radical or an acyl radical, R.sub.2 is hydrogen or a substituted or unsubstituted aliphatic hydrocarbon radical, Y is oxygen or sulphur, n.sub.1 and n.sub.2 each are values of 1 to 3, n. sub.1 +n.sub.2 being at most four, and Ar is a substituted or unsubstituted aromatic hydrocarbon radical, and the acid addition salts, in particular the pharmaceutically acceptable acid addition salts thereof. The new substances posss valuable pharmacological properties, in particular antidepressant activity, and can be ud for the treatment of mental depressions. Specific embodiments are trans- and cis-3-hydroxy-4- (3,4-dimethyl-phenoxy)-piperidine, trans-and cis-3-hydroxy-4-(2,3- dimethyl-phenoxy)-piperidine, their 1-methyl derivatives and the pharmaceutically acceptable salts of the substances.
岗位职能申请人：CIBA-GEIGY CORPORATION
代理人：John J. Maitner
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