Major histocompatibility complex class I-specific

更新时间:2023-06-11 19:41:23 阅读: 评论:0

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扇形的面积公式是什么Major histocompatibility complex class I-specific receptors on human natural killer and T投资担保公司
高中助学金申请书lymphocytes.
察言观色近义词期刊名称: Immunological Reviews伤心难过的图片大全
excel加法求和年份: 2010年
恐慌沸腾期号: 第1期
摘要:Summary: Human NK cells express veral specialized inhibitory receptors that recognize major histocompatibility complex (MHC) class I molecules expresd on normal cells. The lack of expression of one or more HLA CLASS I alleles leads to NK-mediated target cell lysis. Receptors specific for groups of HLA-C (p58), HLA-B (p70) and HLA-A (p140) alleles belong to the Ig superfamily with two or three Ig-like domains in their extracellular portion, and a long cytoplasmic tail containing ITIM motifs and associated with a non-polar transmembrane portion. In contrast, the CD94/NKG2-A receptor complex is compod of type II proteins with a C-type lectin domain which displays a more broad speci
ficity for different class I alleles. Recently, activatory forms of the HLA-C-specific receptors have been identified in some donors. They
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