mutated rabies virus and vaccine

更新时间:2023-06-11 06:53:37 阅读: 评论:0

恋恋不舍的反义词专利名称:mutated rabies virus and vaccine
南乡子李珣发明人:伊藤 直人,杉山 誠
长方体的体积公式
申请号:JP2013524703
申请日:20120713
公开号:JPWO2013011942A1
恐龙的种类介绍
有丝分裂前期公开日:
20150223
感恩卡怎么写专利内容由知识产权出版社提供
专利附图:
摘要: The prent invention is highly safe, the provision of effective and low-cost rabies vaccine. A structure protein of rabies virus, at least, is a 273 amino acid other than phenylalanine, 394 other than tyrosine amino acids of the N protein, amino acid position 333 of the G protein other than argini
ne or lysine of N protein variants Rabies virus (eg, in Figure 2, ERA-N273 / 394-G333 strain), to provide such rabies vaccine formulations
containing the mutations rabies virus. In addition to attenuation of the rabies virus by mutagenesis of G-protein 333 amino acids, it is possible to improve the immunogenicity and safety by mutagenesis at amino acid 273-position and 394-position of the N protein.In addition, by mutagenesis on the amino acid at position 273 and 394 of the N protein,since a strong poison of can be prevented even when 194 of the G protein has been
虞山国家森林公园mutated to a lysine, potentially pathogenic recovery by mutation occurs can be reduced, it is possible to further enhance the safety.
申请人:国立大学法人岐阜大学,共立製薬株式会社
地址:岐阜県岐阜市柳戸1番1,東京都千代田区九段南1丁目5番10号
矫捷的近义词
国籍:JP,JP
代理人:丹羽 俊輔
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