专利名称：CELL SELECTIVE PROTEOME LABELING 发明人：GAUTHIER, NICHOLAS,SANDER,
CHRIS,MILLER, MARTIN机器人翻译
申请号：EP13835876
申请日：20130905
失眠按摩什么穴位公开号：EP2893033A4唐伯虎作品
假期最后一天
财务数据分析公开日：
满洲八大姓
20160803
斗志激昂
专利内容由知识产权出版社提供
大学毕业论文
摘要：The invention relates to a method for the Cell Type specific labeling with Amino acid Precursors (CTAP). In particular, the disclod method permits the incorporation of stable isotope-labeled amino acids into the proteome of a vertebrate cell that has been engineered to express an exogenous enzyme that enables the cell to produce an esntial amino acid from its amino acid substrate. The method employs stable isotope-labeled amino acid substrate/precursors from which esntial amino acids bearing the label are generated. The labeled amino acids generated by the transgenic cell not only supports growth but specifically labels proteins of the transgenic cell. Furthermore, the u of different populations of cells expressing different exogenous amino acid-producing enzymes permits differential labeling of the proteomes of the individual cell populations in multicellular environments.
申请人：MEMORIAL SLOAN-KETTERING CANCER CENTER
更多信息请下载全文后查看
