A COMBINATION OF A 5-HT REUPTAKE INHIBITOR AND A h

更新时间:2023-06-08 07:07:17 阅读: 评论:0

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专利名称:A COMBINATION OF A 5-HT REUPTAKE INHIBITOR AND A h5-HT 1B ANTAGONIST
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OR PARTIAL AGONIST
发明人:BERG, Stefan,ROSS, Svante,THORBERG, Seth-Olov
申请号:EP98944375.9
申请日:19980909
公开号:EP1014985A1
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公开日:
耳目濡染
搬砖语录
20000705
专利内容由知识产权出版社提供
daxie摘要:Carrying out the h5-HT1B antagonists of lectivity or partial agonist the prent invention relates to a kind of a kind of 5-HT reuptake inhibitors of the first component (a) of combination and cond of component (two) has formula (I), and wherein X is CH2, O; Y CONH, NHCO; R1 is H, C1-C6 alkyl, C3-C6 naphthenic ba; R2 is H, C1-C6 alkyl, C1-C6 alkoxies, halogen; R3 is (1), (2), (3), CF3; R4 and R5 stands alone as H or C1-C4 alkyl, as racemic modification, R- enantiomers or S- enantiomers, and the form of the component (a) and component (b) is in free bas, solvent or its pharmaceutically acceptable salt, and its preparation, the pharmaceutical preparation containing the compounds of this invention, the combination us and treats the disturbance of emotion such as depression and anxiety and OCD and the combined kit and comprising the combination.
生产物流申请人:AstraZeneca AB
地址:151 85 Södertälje SE
国籍:SE
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