专利名称:Methods for array asmbly and detection
林晓桐involving elongation of lf-complementary
多层蛋糕looped probes
泰坦甲虫发明人:Michael Seul,Yi Zhang,Sukanta梦见打雷下雨
Banerjee,Jiacheng Yang,Chiu Chau
申请号:US14449569
宝宝吐奶原因申请日:20140801
敬仰的反义词公开号:US09670534B2
公开日:专八考试时间
20170606
专利内容由知识产权出版社提供
专利附图:
恶字成语摘要:Disclod herein are methods for array asmbly and detection. The methods
can u an incubation chamber containing a suspension of nucleic acid targets, polymera and a t of oligonucleotide probes bound to magnetic beads in a randomly disperd state. Each probe can have a target binding domain that is complementary to a target nucleic acid, a closing domain with a quence that is complementary to the quence of the target binding domain, and a joining region between the binding domain and the closing domain, which is not complementary to the target nucleic acid. Method steps can include providing the incubation chamber, placing the incubation chamber in a magnetic trap, generating a magnetic field that induces the magnetic beads to migrate towards a substrate and, once in proximity to the substrate, to interact with each other repulsively and reorganize into arrays, and imaging the array.
申请人:BioArray Solutions, Ltd.
地址:Warren NJ US
国籍:US
代理机构:Mintz, Levin, Cohn, Ferris, Glovsky and Popeo P.C.
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