专利名称：Dark quenchers for fluorescence resonance energy transfer (FRET) in bioassays
发明人：Wensheng Xia,David Whitten,Duncan
McBranch
申请号：US10945097我与妹妹
宁波溪口申请日：20040921
公开号：US20050118619A1
word更新目录公开日：
20050602
专利内容由知识产权出版社提供凉面的热量
党员教师工作总结摘要：Non-fluorescent dyes (i.e., dark quenchers) which can be ud to quench the fluorescence of energy donors in bioassays through fluorescence resonance energy transfer (FRET) are described. The dark quenchers can be associated with (e.g., conjugated to) peptides, proteins, antibodies, DNA/RNA, or other biological molecules or receptors or complexed to metal containing compounds to develop bioassays bad on donor-acceptor energy transfer. Bioassays are also described wherein an increa or a decrea in paration distance between a fluorescent donor compound and a dark quencher or dark quencher conjugate is detected. Kits including the dark quenchers or dark quencher conjugates are also described.
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申请人：Wensheng Xia,David Whitten,Duncan McBranch
地址：Santa Fe NM US,Albuquerque NM US,Santa Fe NM US
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国籍：US,US,US
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