专利名称:Methods of screening heteromeric
贵系鲁班的故事T1R2/T1R3 receptors for compounds which
modulate sweet taste signaling
发明人:Jon E. Adler,Xiaodong Li,Lena
蝶恋花歌曲原唱Staszewski,Hong Xu,Fernando Echeverri
申请号:US13357110
服字开头的成语申请日:20120124
公开号:US08809000B2
公开日:
什么的高原20140819
专利内容由知识产权出版社提供
五分熟英文摘要:Newly identified mammalian taste-cell-specific G protein-coupled receptors which function as hetero-oligomeric complexes in the sweet taste transduction pathway, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in sweet taste signaling as hetero-oligomeric complexes, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for identifying putative taste modulating compounds using such hetero-oligomeric complexes also described, as is a novel surface expression facilitating peptide uful for targeting integral plasma membrane proteins to the surface of a cell.
幻璃镜
申请人:Jon E. Adler,Xiaodong Li,Lena Staszewski,Hong Xu,Fernando Echeverri
地址:San Diego CA US,San Diego CA US,San Diego CA US,San Diego CA US,Chula Vista CA US
国籍:US,US,US,US,US
代理机构:LeClairRyan, a professional corporation 代理人:Robin L. Teskin
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