Identification of an alternative 5′-untranslated exon and new polymorphisms of angiotensin-converting enzyme 2 gene: Lack of association with SARS in the
Vietname population
浪费原唱期刊名称： American Journal of Medical Genetics Part A
社保基数和工资的关系>贺的组词是什么
作者： Satoru Itoyama,Naoto Keicho,Minako Hijikata,Tran Quy,Takehiko Sasazuki
年份： 2010年
期号： 第1期
关键词： angiotensin‐converting enzyme 2 (ACE2;vere acute respiratory写思乡的古诗
syndrome (SARS;SARS associated coronavirus (SARS Co‐V;virus
receptor;polymorphism;association study
摘要：We analyzed genetic variations of angiotensin-converting enzyme 2 (ACE2), considering that it might influence patients' susceptibility to vere acute
respiratory syndrome-associated coronavirus (SARS-CoV) or development of SARS as a functional receptor. By cloning of the full-length cDNA of the ACE2 gene in the lung, where replication occurs on SARS-CoV, it was shown that there are different splicing sites. All exons including the new alternative exon, exon-intron boundaries, and the corresponding 5-flanking region of the gene were investigated and 19
熙熙攘攘皆为利来
single nucleotide polymorphisms (SNPs) were found. Out of the, 13 SNPs
including one non-synonymous substitution and three 3-UTR polymorphisms were newly identified. A ca control study involving 44 SARS cas, 16 anti-SARS-CoV
青陵台antibody-positive contacts, 87 antibody-negative contacts,...
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