专利名称:NEW DIPHOSPHONIC ACID DERIVATIVES CONTAINING AMIDINE GROUPS, PROCESS
FOR PREPARING THEM AND DRUGS
CONTAINING THESE COMPOUNDS
发明人:BOSIES, Elmar,ZILCH, Harald嘉和城温泉谷
带日的诗句>炖牛排申请号:EP90914709.0
申请日:19900901
公开号:EP0491001A1
公开日:
民主测评19920624
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牙疼吃什么食物摘要: Compounds of formula (I), wherein R is H or C1-C4 alkyl, R1 reprents hydrogen, C1-C6 alkyl, aryl, alkyl aryl, C1-C4 alkylamino C1-C6 alkylamino C1-C6 C1-C4 alkyl, dialkylamino C1-C6 alkyl C1-C4, alkoxy C1-C4 C1-C4 alkyl, alkylthio C1-C4 C1-C4 alkyl, alkenyl C3-C7, R2 is R1 or alkenyl, C2-C7 alkylmercapto C1-C6 alkyl, C1-C6 alkoxy alkyl phenoxy C1-C4alkyl, amino, C1-C4 di-alkylamino C1-C4 alkyl, morpholino, thiomorpholino, pyrrolidino, piperidine, hexamethyleneimino, pyrazolino, imidazolino, n = 0, 1 or 2 and R1 and R2 together with the carbon atom and the nitrogen atom to which they are attached may form a heterocyclic compound pentagonal, hexagonal or heptagonal with 1 to 4 hetero atoms wherein the hetero atoms may be the same or different and reprent oxygen, nitrogen or sulfur and the cyclic compound is optionally substituted with one or more alkyl C1-C6, C1-C6 alkoxy, alkylmercapto C1-C 6, by hydroxy, amino, nitro, halogen or halomethyl, as well as their pharmacologically neutral salts, are uful for treating calcium metabolism disorders. Also disclod are a process for their manufacture and medicaments containing the compounds.
申请人:BOEHRINGER MANNHEIM GMBH 地址:D-68298 Mannheim DE
国籍:DE
如何正确佩戴口罩代理机构:Weber, Manfred, Dr., et al
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