专利名称:Preparation of 2,3-trans-1,4-bridged
cyclohexane sulfonamide derivatives and
their u董永故里
福特f650
国画枇杷发明人:Narisada, Masayuki,Watanabe,
Fumihiko,Ohtani, Mitsuaki,Kawata, Kyozo 申请号:EP89313124.3
申请日:19891214
公开号:EP0373951B1
公开日:
简短座右铭
19930324
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网速太慢怎么办摘要:A process for preparing a 2,3-trans-1,4-bridged cyclohexane sulfonamide derivative of Formula (I): wherein R is phenyl or phenyl substituted with hydroxy, lower alkoxy, halogen or lower alkyl; Y is unsubstituted or substituted methylene, ethylene, vinylene or oxygen; m is 0 or 1; n is 0, 1 or 2 with the proviso that when m is 0, n is not 0, and when m is 1, n is not 2, in which a cis/trans mixture of 1,4-bridged cyclohexane sulfonamides of Formula (I) min : wherein R, Y, m and n are as defined above, in a mixture of water and an organic solvent at pH 3 - 7, is reacted with an anionoid reagent or a water-soluble carbonyl reagent to form a water-soluble adduct only with the trans isomer of said sulfonamide (I), and in which the resulting compound of Formula (I) is parated in the form of said water-soluble adduct with said anionoid reagent or water-soluble carbonyl reagent.
申请人:SHIONOGI SEIYAKU KABUSHIKI KAISHA TRADING UNDER THE NAME OF SHIONOGI & CO. LTD.
手机消费地址:1-8, DOSHOMACHI 3-CHOME CHUO-KU; OSAKA 541
代理机构:Hardisty, David Robert 更多信息请下载全文后查看