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教研室是干什么的>耳朵后面长痣巯嘌呤类药物用于儿童急性淋巴细胞性白血病患者个体化治疗的研究进展
六用英语怎么写摘要 急性淋巴细胞性白血病(acute lymphoblastic leukemia, ALL)是儿童期发病率最高的恶性肿瘤类型之一。目前,对ALL患儿维持治疗阶段的化疗多以持续口服巯嘌呤为主。使用巯嘌呤类药物前检测患儿硫嘌呤S-甲基转移酶的基因型或活性,据此调整药物剂量、实现个体化治疗可提高ALL的治愈率。本文就巯嘌呤类药物用于ALL患儿个体化治疗的研究进展作一综述。
颤栗拼音香燐ABSTRACT Acute lymphoblastic leukemia (ALL) is one of the tumors with the highest incidence in childhood. Sustaining oral mercaptopurine has currently been the main therapy in chemotherapy of ALL in the maintenance pha. The do of mercaptopurine can be adjusted bad on the determination of thiopurine S-methyltransfera genotype or thiopurine S-methyltransfera activity before medication so as to achieve individual treatment and the improvement of cure rate. In this paper, the rearch advance of mercaptopurine drugs in the individualized treatment of children with ALL is reviewed.
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