STATE OF CALIFORNIA
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986
CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITY
FEBRUARY 5, 2010
The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revi and republish at least once per year the list of chemicals known to the State to cau cancer or reproductive toxicity. The identification number indicated in the following list is the Chemical安全生产专项整治
Abstracts Service (CAS) Registry Number. No CAS number is given when veral substances are prented as a single listing. The date refers to the initial appearance of the chemical on the list. For easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subquently been removed.
Chemical Type of Toxicity CAS No. Date Listed A-alpha-C (2-Amino-9H-pyrido [2,3-b]indole) cancer 26148-68-5 January 1, 1990 Acetaldehyde cancer 75-07-0 April 1, 1988 Acetamide cancer 60-35-5 January 1, 1990 Acetazolamide developmental 59-66-5 August 20, 1999 Acetochlor cancer 34256-82-1 January 1, 1989 Acetohydroxamic acid developmental 546-88-3 April 1, 1990 2-Acetylaminofluorene cancer 53-96-3 July 1, 1987 Acifluorfen sodium cancer 62476-59-9 January 1, 1990 Acrylamide cancer 79-06-1 January 1, 1990 Acrylonitrile cancer 107-13-1 July 1, 1987 Actinomycin D cancer 50-76-0 October 1, 1989 developmental October 1, 1992 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] acrylamide cancer 3688-53-7 July 1, 1987 Aflatoxins cancer --- January 1, 1988 Alachlor cancer 15972-60-8 January 1, 1989 Alcoholic beverages, when associated
with alcohol abu cancer --- July 1, 1988 Aldrin cancer 309-00-2 July 1, 1988 All-trans retinoic acid developmental 302-79-4 January 1, 1989 Allyl chloride Delisted October 29, 1999 cancer 107-05-1 January 1, 1990 Alprazolam developmental 28981-97-7 July 1, 1990 Altretamine developmental, male 645-05-6 August 20, 1999 Amantadine hydrochloride developmental 665-66-7 February 27, 2001 Amikacin sulfate developmental 39831-55-5 July 1, 1990 2-Aminoanthraquinone cancer 117-79-3 October 1, 1989 p -Aminoazobenzene cancer 60-09-3 January 1, 1990 o -Aminoazotoluene cancer 97-56-3 July 1, 1987
4-Aminobiphenyl (4-amino- diphenyl)
cancer 92-67-1 February 27, 1987 1-Amino-2,4-dibromo- anthraquinone
cancer 81-49-2 August 26, 1997 3-Amino-9-ethylcarbazole hydrochloride cancer 6109-97-3 July 1, 1989 2-Aminofluorene cancer
153-78-6 January 29, 1999 Aminoglutethimide developmental 125-84-8 July 1, 1990 Aminoglycosides
developmental ---
October 1, 1992 1-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 1989 2-Amino-5-(5-nitro-2-furyl)-1,3,4- thiadiazole
cancer
712-68-5 July 1, 1987 4-Amino-2-nitrophenol cancer
119-34-6 January 29, 1999 Aminopterin
developmental, female 54-62-6 July 1, 1987 Amiodarone hydrochloride developmental, female, male
19774-82-4 August 26, 1997 Amitraz developmental 33089-61-1 March 30, 1999 Amitrole cancer
61-82-5 July 1, 1987 Amoxapine developmental 14028-44-5 May 15, 1998 Amsacrine
cancer
51264-14-3 August 7, 2009
tert-Amyl methyl ether developmental 994-05-8 December 18, 2009 Anabolic steroids
female, male --- April 1, 1990
Analgesic mixtures containing phenacetin
cancer --- February 27, 1987 Angiotensin converting enzyme (ACE) inhibitors developmental --- October 1, 1992 Aniline
cancer 62-53-3 January 1, 1990 Aniline hydrochloride cancer 142-04-1 May 15, 1998 o -Anisidine
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cancer 90-04-0 July 1, 1987 o -Anisidine hydrochloride cancer
134-29-2 July 1, 1987 Anisindione
developmental 117-37-3 October 1, 1992 Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990 Anthraquinone cancer 84-65-1 September 28, 2007 Aramite cancer 140-57-8 July 1, 1987
Areca nut
cancer --- February 3, 2006 Aristolochic acids
cancer --- July 9, 2004
Arnic (inorganic arnic compounds)
cancer
-- February 27, 1987 Arnic (inorganic oxides) developmental ---
May 1, 1997
Asbestos
cancer
1332-21-4 February 27, 1987 Aspirin (NOTE: It is especially important not to u aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician becau it may cau problems in the unborn child or
complications during delivery.) developmental, female
50-78-2
减肥一周食谱
July 1, 1990
Atenolol developmental 29122-68-7 August 26, 1997 Auramine cancer
492-80-8 July 1, 1987
Auranofin developmental 34031-32-8 January 29, 1999 Azacitidine
cancer 320-67-2 January 1, 1992
Azarine cancer 115-02-6
July 1, 1987
Azathioprine
cancer
developmental
446-86-6 February 27, 1987 September 1, 1996 Azobenzene cancer 103-33-3 January 1, 1990
Barbiturates developmental ---
October 1, 1992 Beclomethasone dipropionate developmental 5534-09-8 May 15, 1998 Benomyl developmental, male 17804-35-2 July 1, 1991 Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008 Benz[a]anthracene cancer 56-55-3 July 1, 1987
Benzene cancer
developmental, male
71-43-2 February 27, 1987 December 26, 1997 Benzidine [and its salts] cancer 92-87-5 February 27,
1987 Benzidine-bad dyes cancer --- October 1, 1992 Benzodiazepines developmental ---
October 1, 1992 Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987 Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987 Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987 Benzofuran cancer 271-89-6 October 1, 1990 Benzo[a]pyrene cancer 50-32-8 July 1, 1987 Benzotrichloride cancer 98-07-7 July 1, 1987 Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990 Benzyl chloride cancer 100-44-7 January 1, 1990 Benzyl violet 4B cancer 1694-09-3 July 1, 1987 Beryllium and beryllium compounds cancer --- October 1, 1987 Betel quid with tobacco cancer --- January 1, 1990 Betel quid without tobacco cancer ---
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February 3, 2006 2,2-Bis(bromomethyl)-1,3- propanediol
cancer 3296-90-0 May 1, 1996 Bis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988
N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine)
cancer
494-03-1 February 27, 1987 Bischloroethyl nitrosourea (BCNU) (Carmustine) cancer developmental 154-93-8 July 1, 1987 July 1, 1990
Bis(chloromethyl)ether cancer
542-88-1 February 27, 1987 Bis(2-chloro-1-methylethyl)ether,
technical grade
cancer --- October 29, 1999 Bitumens, extracts of steam-refined and air refined cancer ---
January 1, 1990 Bracken fern cancer ---
January 1, 1990 Bromacil lithium salt developmental
male
53404-19-6 May 18, 1999 January 17, 2003 Bromate cancer 15541-45-4 May 31, 2002 Bromodichloromethane cancer 75-27-4 January 1, 1990 Bromoethane cancer 74-96-4 December 22, 2000 Bromoform cancer 75-25-2 April 1, 1991
1-Bromopropane (1-BP) developmental, female,
male
106-94-5 December 7, 2004 2-Bromopropane (2-BP) female, male 75-26-3 May 31, 2005 Bromoxynil developmental 1689-84-5 October 1, 1990 Bromoxynil octanoate developmental
1689-99-2
May 18, 1999
Butabarbital sodium developmental 143-81-7 October 1, 1992 1,3-Butadiene cancer
106-99-0 April 1, 1988 1,3-Butadiene
developmental, female, male 106-99-0 April 16, 2004 1,4-Butanediol dimethanesulfonate (Busulfan)
cancer
developmental 55-98-1 February 27, 1987 January 1, 1989 Butylated hydroxyanisole cancer
25013-16-5 January 1, 1990 Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005 n-Butyl glycidyl ether male 2426-08-6 August 7, 2009 beta-Butyrolactone cancer 3068-88-0 July 1, 1987
Cacodylic acid cancer
75-60-5 May 1, 1996 Cadmium
developmental, male --- May 1, 1997 Cadmium and cadmium compounds cancer
--- October 1, 1987 Caffeic acid cancer 331-39-5 October 1, 1994 Captafol cancer 2425-06-1 October 1, 1988 Captan
cancer
133-06-2 January 1, 1990 Carbamazepine developmental 298-46-4 January 29, 1999 Carbaryl cancer
63-25-2 February 5, 2010 Carbaryl developmental, male 63-25-2 August 7, 2009 Carbazole
cancer 86-74-8 May 1, 1996
Carbon black (airborne, unbound particles of respirable size) cancer
1333-86-4 February 21, 2003 Carbon disulfide
developmental, female, male
75-15-0 July 1, 1989 Carbon monoxide developmental 630-08-0 July 1, 1989 Carbon tetrachloride cancer 56-23-5 October 1, 1987 Carbon-black extracts cancer
---
January 1, 1990 Carboplatin
developmental 41575-94-4 July 1, 1990
N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002 Catechol
cancer 120-80-9 July 15, 2003 Ceramic fibers (airborne particles of respirable size)
cancer --- July 1, 1990 Certain combined chemotherapy for lymphomas cancer --- February 27, 1987 Chenodiol developmental 474-25-9 April 1, 1990
Chlorambucil
cancer
developmental 305-03-3 February 27, 1987 January 1, 1989 Chloramphenicol
cancer
56-75-7 October 1, 1989 Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987 Chlordane
cancer 57-74-9 July 1, 1988 Chlordecone (Kepone) cancer
developmental 143-50-0 January 1, 1988 January 1, 1989 Chlordiazepoxide
developmental 58-25-3 January 1, 1992 Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992 Chlordimeform cancer 6164-98-3 January 1, 1989 Chlorendic acid
cancer 115-28-6 July 1, 1989 Chlorinated paraffins (Average Chain length, C12; ap- proximately 60 percent chlorine by weight)
cancer
108171-26-2
July 1, 1989
p -Chloroaniline
cancer 106-47-8 October 1, 1994 p -Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998 Chlorodibromomethane Delisted October 29, 1999 cancer 124-48-1 January 1, 1990 Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990 1-(2-Chloroethyl)-3-cyclohexyl- 1-nitrosourea (CCNU) (Lomustine)
cancer
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developmental 13010-47-4 January 1, 1988 July 1, 1990 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)
-1-nitrosourea (Methyl-CCNU) cancer 13909-09-6 October 1, 1988 Chloroform cancer
67-66-3 October 1, 1987 Chloroform
developmental 67-66-3 August 7, 2009 Chloromethyl methyl ether (technical grade)
cancer 107-30-2 February 27, 1987 3-Chloro-2-methylpropene cancer 563-47-3 July 1, 1989
1-Chloro-4-nitrobenzene
cancer 100-00-5 October 29, 1999 4-Chloro-o -phenylenediamine cancer 95-83-0 January 1, 1988 Chloroprene
cancer 126-99-8 June 2, 2000 2-Chloropropionic acid male 598-78-7 August 7, 2009 Chlorothalonil
cancer 1897-45-6 January 1, 1989 p -Chloro-o -toluidine
cancer 95-69-2 January 1, 1990 p-Chloro-o -toluidine, strong acid salts of
cancer --- May 15, 1998 5-Chloro-o -toluidine and its strong acid salts cancer服务内容怎么写
---
特物资October 24, 1997 Chlorotrianine cancer 569-57-3 September 1, 1996 Chlorozotocin cancer
54749-90-5 January 1, 1992 Chlorsulfuron
developmental, female, male
64902-72-3 May 14, 1999 Chromium (hexavalent compounds) cancer
丹霞山风景名胜区
--- February 27, 1987 Chromium (hexavalent compounds) developmental female,
male
--- December 19, 2008 Chryne cancer 218-01-9 January 1, 1990 C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992 C.I. Basic Red 9 monohydrochloride cancer 569-61-9 July 1, 1989 C.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997 C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997 C.I. Solvent Yellow 14 cancer 842-07-9 May 15, 1998 Ciclosporin (Cyclosporin A; Cyclosporine) cancer 59865-13-3 79217-60-0 January 1, 1992 Cidofovir cancer, developmental,
female, male
113852-37-2 January 29, 1999 Cinnamyl anthranilate cancer 87-29-6 July 1, 1989 Cisplatin cancer 15663-27-1 October 1, 1988 Citrus Red No. 2 cancer 6358-53-8 October 1, 1989 Cladribine developmental 4291-63-8 September 1, 1996 Clarithromycin developmental 81103-11-9 May 1, 1997 Clobetasol propionate developmental, female 25122-46-7 May 15, 1998
Clofibrate cancer 637-07-0 September 1, 1996 Clomiphene citrate developmental 50-41-9 April 1, 1990 Clorazepate dipotassium developmental
57109-90-7
October 1, 1992