素炒西地那非的生殖毒性研究进展
作者：黄嬿 吴建辉小孩晚上睡觉磨牙
三大改造的实质来源：《中国医药导报》2015年第20期水东老街
爱在午夜降临前 [摘要] 西地那非作为第一个用于治疗阴茎勃起功能障碍的Ⅴ型磷酸二酯酶抑制剂，其人群使用范围非常广泛，但其是否影响生育存在争议。本文就国内外有关西地那非雄性生殖毒性的实验动物及人群研究结果进行了综述，结果表明，长期使用西地那非可能对前列腺、睾丸和阴茎组织产生不良影响，并影响精子功能导致不育，其对前列腺的作用值得深入研究。
[关键词] 西地那非；生殖毒性；磷酸二酯酶抑制剂尼字组词
鞋子的品牌有哪些 [中图分类号] R969.4 [文献标识码] A [文章编号] 1673-7210（2015）07（b）-0027-04
大黑枣 [Abstract] As the first PDE5 inhibitor to treat erectile dysfunction， Sildenafil is widely ud in humans all over the world， however， it is still argued whether Sildenafil can induce infertility. In this paper， all the recently published articles of experimental animal an
d human being rearch on the male reproductive toxicity induced by Sildenafil at home and abroad are summarized. It is suggested that Sildenafil will bring adver effects to prostate， testis and penis after long-time using， and it will also result in infertility by affecting sperm function， moreover， the relationship between Sildenafil and prostate is worth to be further developed.
