医学免疫学英语试题
ⅠChoo one which is the best answer in each question(40 × 1 point
= 40 )
1. Immunological unresponsiveness to lf antigens is called: ( A)
A Tolerance
B Tolerogen
C Memory
D Acquired
immunity
列数字2. The signal transduction molecules associated with BCR are (B )
A. CD21 and CD81.
B. Igαnd IgβCD79a,b
C. IgD and IgM. and ITIMs.
3. T cells are MHC-restricted in their ability to respond to antigen becau (D )
A. all antigen must be procesd and prented to activate lymphocytes.
B. during an infection, all cells in the body prent antigen on MHC Class
I.
C. MHC binds antigen more specifically than TCR does.
D. TCR must recognize both antigen and MHC molecules.
4. An antibody Fab contains ( A B)
A. complementarity determining regions.
B. H and L chain variable regions.
C. one antigen binding region.
D. one H-L interchain disulfide bond.
5 Positive lection in the thymus is mediated by: ( A )
A Thymic epithelial cells.
B Macrophages.
C Dendritic cells.
D B-cells.
6. Type Ⅳ hyperntivity is often referred to as: ( B )
A. Immediate hypernsitivity
B. Delayed hypernsitivity
C. Cytotoxic hypernsitivity
A. Immediate hypernsitivity
B. Delayed hypernsitivity
C. Cytotoxic hypernsitivity
D. Allergic hypernsitivity
8. Naive B cell express ( C )
A. IgA alone and IgG C IgM +IgD and Ig
9. T cell-derived cytokines ( D )
A. are antigen-specific products of T cell activation
B. are stored in the resting T cell and relead on activation
C. are MHC-restricted in their effects
D. influence the class of antibodies produced by B cell
10.Neutrophils are attracted to an infected area by ( C )
A. IgM
B. C1
C. C5a
D. C8
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plement lys cells by ( C )
A. enzymatic digestion of the cell membrane
B.activation of adenylate cycla
C.inrtion of complement proteins into the cell membrane
D.inhibition of elongation factor 2
12. CD8 is a marker of ( C)
A. B cells
B. Helper - T cells
C. cytotoxic T cell
D. Mφ
13. MHC class Ⅱ molecules are found on (B )
A. Virtually all cells in the body
B. B cells, DC and Mφ
C. Virtually all nucleated cells in the body
D. Only on virally-infected cells.
14. All of following cytokines are creted by Th2 cells except (B )
A. IL-4
D. IL-6
15. Which of the following is NOT true of CD4+and CD8+cell markers? ( D )
A. The are both surface glycoproteins expresd on T-cells.
B. The rve to distinguish different types of T-cells, ., helper, suppressor and cytotoxic, from each other.
C. The are not found associated with immunoglobulins.
D. Both of the markers are prent on ALL T-cells.
16. Cells bearing MHC class I plus peptide are targets for specific:
( B )
A B-cells.
B Cytotoxic T-cells.
C Th1 cells.
D Th2 cells.
17. Dendritic cells are characterized by: ( D )
A the prence of major basic protein
B expression of CD3
C expression of IgM molecules
D their interface between the
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innate and adaptive immune system
18. Which of the following uniquely distinguishes the T-cell receptor (TCR)
from an antibody? ( A )
A. The TCR can bind an antigen fragment only in a trimolecular complex
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with either the class I or class II surface proteins of the major histocompatibility complex
B. The TCR can function as a cell surface antigen receptor
C. The TCR is compod of two different types of polypeptide chains
D. The TCR is capable of participating in a cytotoxic reaction.
19. A critical property of an antigen is ( A )
A. Its ability to stimulate an immune respon
B. a unique topological feature called an paratope
C. not a unique topological feature called an antigenic determinant
D. the size of which is relatively small
of bacteria occurs through coating bacteria just with: ( A )
A C3b
B C8
C Membrane attack complex
21. The following is characteristic of B- but not T-cells: ( D )
A Class I MHC.
B CD3.
C HIV virus receptor.
D Surface immunoglobulin.
22.Which of the following molecules is expresd on the surface of mature CD4+T cells? ( C )
A. B cell receptor
B. CD1d
23. The thymus is the site of initial differentiation for ( D )家乡美
A. B cells
B. Erythrocytes
C. Hematopietic stem cells
D. T
cells
贫困证明怎么开24. The membrane attack complex consists of: ( C )
A OH
B C3b3b,Bb
C C5b,6,7,8,9
D Properdin
25. Typ e Ⅰhyperntivity is often referred to as: (A )
A. Immediate hypernsitivity
B. Delayed hypernsitivity
C. Cytotoxic hypernsitivity
D. Immune complex hypernsitivity
26. Type Ⅲ hyperntivity is often referred to as: ( D)
打破沙锅璺到底A. Immediate hypernsitivity
B. Delayed hypernsitivity
C. Cytotoxic hypernsitivity
D. Immune complex hypernsitivity
27. The typeⅠhyperntivity is mediated by: ( D )
A. IgA
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B. IgD
C. IgG
28. The cytokine which is most involved in the class switch to IgE production is: ( D ) beta
29. Which type hypernsitivity is related to the mechanism of acute
Arthus reaction: ( C )
A. Type Ⅰhyperntivity
B. Type Ⅱhyperntivity
C. Type Ⅲ hyperntivity
D. Type Ⅳ hyperntivity
30. T-cell CD40L provides a costimulatory signal to B-cells by ligating: ( A )
A CD40
B MH
C class II C CD28
D CD19
31. Which immunoglobulin can be transported through the placenta? ( A )
A. IgG
B. IgM
C. Secretory IgA
D. IgE
32. Which immunoglobulin is the most one in the blood? ( A )
A. IgG
B. IgM
C. Secretory IgA
D. IgE
33. Which immunoglobulin can mediate the immediate hypernsitivity? ( D )
A. IgG
B. IgM
C. Secretory IgA
D. IgE
李宗瑶34. Molecules directly involved in NK cell mediated killing include: ( B )
A nitric oxide
B granzyme
C complement
D IFN-γ
35. Immune complexes consist of ( C )