C1-INH concentrate for treatment of acute hereditary angioedema: a pediatric cohort from the日本cosme
I.M.P.A.C.T. studies.
期刊名称： Pediatric Allergy & Immunology
作者： Schneider, Lynda,Hurewitz, David,Wasrman, Richard,Obtulowicz,声之形简介
死要面子fn键设置Krystyna,Machnig, Thomas,Moldovan, Dumitru,Reshef, Avner,Craig, Timothy J.
年份： 2013年
期号： 第1期
关键词： acute attacks of hereditary angioedema; Berinert; C1-INH; hereditary
angioedema; pdC1-INH; pediatric and adolescent patients; plasma-derived C1-
estera inhibitor致四年后的自己
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摘要：BackgroundWe analyzed the clinical respon of pediatric and adolescent hereditary angioedema (HAE) patients to pdC1-INH in the International Multicenter Prospective Angioedema C1-INH Trials (I.M.P.A.C.T.) 1 and 2.MethodsPatients included in this post hoc analysis of prospectively collected data were between 10 and 18 yr old with type I or II HAE and a documented history of abdominal or facial attacks. Patients received a single injection of pdC1-INH concentrate (Berinert, CSL Behring, Marburg, Germany) 20 U/kg. Efficacy end-points were time from the administration of study drug to ont of symptom relief and time to complete
英语作文模板relief of all symptoms.ResultsSeven pediatric patients were included in I.M.P.A.C.T.1 with only 1 attack analyzed per patient. Median time to ont of relief was 0.42 h and to complete resolution was 8.08 h. No...
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