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DOI :10.3969/j.issn.1671-4695.2019.05.029文章编号:1671-4695(2019)05-0541-05
单心动周期冠脉CTA 的个体化三期扫描造影剂注射方案研究原媛钟朝辉*王振常张婷婷张景东(首都医科大学附属北京友谊医院放射科北京100050)
基金项目:科技北京百名领才培养工程(编号:Z141107001514002);北京市医院管理局"使命"人才计划(编号:SML20150101);
北京学者计划(编号:京人社专家发
〔2015〕160号)*通讯作者:钟朝辉,E -mail :laijinyuxuan12@sina.com 【摘要】目的探讨个体化三期注射造影的方案在单心动周期成像的冠状动脉CT 血管造影(CCTA )中的作用。方法前瞻性收集2018年3 8月首都医科大学附属北京友谊医院收治的106例行CCTA 扫描的患者,将患者按照随机数字表法分为两组:A 组(n =54)患者采用个体化三期造影剂注射方案,患者总碘量根据患者体重进行计算为体重(kg )ˑ0.21gI /kg +2.1gI ;B 组(n =52)患者采用固定剂量的碘造影剂的造影剂注射方案,患者总碘量固定为17.5gI 。对重建图像的冠脉血管和心脏解剖结构分别进行客观和主观评价。结果A 组患者的平均碘量为16.48ʃ2.43gI 低于B 组患者的平均碘量17.5ʃ0.00gI (P <0.05)。对于右心室的显影,A 组中52例(96.3%)的造影剂强化程度>140HU ,均达到对右心解剖结构的诊断需要;B 组中3例(5.8%)强化程度>140HU ,右心解剖结构达到诊断要求的占28.8%。对于冠脉血管的CT 值,A 组明显低于B 组,两组在主观评价结果方面差异无统计学意义(P >0.05)。A 组患
脖子上长痘痘是什么原因引起的者高体重(≥75kg )和中低体重(<75kg )之间各个解剖结构的造影剂强化差异无统计学意义(P >0.05),企业网站策划
B 组患者差异具有统计学意义(P <0.05)。结论在单心动周期的冠脉CTA 中个体化三期造影剂注
射方案较传统固定剂量双期注射方案对冠脉血管的强化更为稳定,能够更好地显示右心系统的解剖结构,同时造影剂整体用量更低。
【关键词】冠状动脉CT 血管造影造影剂注射剂量冠脉血管心脏解剖结构
Study on the application of individualized split -bolus of contrast medium injection protocol in coronary CT angiography.YUAN Yuan ,ZHONG Zhao -hui ,WANG Zhen -chang ,et al.Department of Radiology ,Beijing Friendship Hospital ,Capital Medical University ,Beijing 100050,China.
【Abstract 】Objective To explore the effect of individualized split -bolus of contrast medium (CM )injection protocol in one -beat coro-
nary CT angiography (CCTA )examination.Methods
A total of 106patients referred to undergo CCTA examination in this hospital during March to August in 2018were prospectively enrolled and they were randomly divided into two groups.Patients in group A (n =54)received an individu-alized split -bolus of CM injection protocol.The iodine dosage was calculated according to the weight of patients ,that is the weight of patients (kg )ˑ0.21gI /kg +2.1gI.Patients in group
批量打印B (n =52)received injection with fixed CM dosage (17.5gI ).Objective and subjective evalua-tion of coronary artery and cardiac anatomical structure in reconstructed images was performed.Results The average CM dosage in group A is lower than that of group B (16.48ʃ2.43gI vs.17.5ʃ0.00gI ,P <0.05).In group A ,52cas (96.3%)achieved a satisfactory enhance-ment in right ventricle (CT value was greater than 140HU )and the visualization of right ventricle fulfilled the diagnostic requirement.In group B ,3(5.8%)patients achieved 140HU enhancement and 15cas (28.8%)fulfill the diagnostic requirement.As to the enhancement of coronary arteries ,CT value in group A was significantly lower than that of group B (P <0.05).There was no significant difference in subjective scoring between the two groups (P >0.05).In group A ,there was no significant difference in enhancement of main cardiac anatomical structure be-tween patients with high body weight (≥75kg )and low body weight (<75kg )(P >0.05).In group B ,the difference between high and low body weight patients was significant (P <0.05).Conclusion
In one -beat CCTA ,comparing with the traditional injection protocol with fixed CM dosage ,individualized spit -bolus CM injection protocol can achieve a more efficient u of contrast agency ,more stable coronary artery en-
酷狗歌曲
hancement and better visualization of right ventricles.
【Key words 】Coronary computed tomography angiography ;Right ventricle ;Objective asssment ;Subjective asssment ;Cardiac anatomi-cal structure ·145·临床和实验医学杂志2019年3月
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