铜催化的sp3c-h氧化反应和镍催化的kumada交叉偶联反应的研究

更新时间:2023-05-22 11:48:11 阅读: 评论:0

㈨㈣㈣洲㈣洲㈣lllIl矾
ABSTRACTY232597
温暖的怀抱TheC.Hoxidationreactionsareimportantandefficientmethodsfor
恋人手中樱花草
formingC.Cbondsinorganicchemistry.Thecross—couplingreactionsoforganicelectrophilicreagentswithorganicmetalnucleophilicreagents
of
arealsooneofthemostimportantmethodsfortheconstruction
carbon-carbonbonds.Thesemethodsenablenewapproachestocomplex
organic
普通感冒症状organiccompoundsincludingnaturalproducts,valuable
檐的读音
intermediates,biologicallyactivereagentsandfunctionalorganicmaterials.Thedissertationincludedtwopartsofworks:(1)
Copper-catalyzedC—Hoxidationcross—couplingofa—aminocarbonyl
compounds;(2)Nickel—catalyzedKumadareactionoftosylalkaneswithGrignardreagentstoproducealkenesandmodifiedarylketones.Themain苦丁茶
contentsofthisdissertationaresummarizedasfollow:
1.RecentprogressinCu-catalyzedsp3C—Hoxidationreactionsis
记忆中的芬芳
summarized.ImportantlythemaincontentisthereviewofCu-catalyzed
reactionstoconstructtheC—Cbonds.
sp3C—Hoxidationcross-coupling
2.Anovelandmildroutetotheselectivesynthesisof2-(1H-indol一3-y1)-2一imino—carbonylsand2-(1H-indol一3一y1)一2一OXO—
carbonylshasbeenreportedbyCu·-catalyzedC··H
oxidation/cross..couplingofa--aminocarbonylcompoundswithindolesin
thepresenceoftert-butylhydroperoxide(TBHP).Thisreactionis
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