专利名称：TRIAZA-SPIROPIPERIDINE DERIVATIVES FOR USE AS GLYT-1 INHIBITORS IN THE抚顺美食
TREATMENT OF NEUROLOGICAL AND
尖吻蝮蛇
NEUROPSYCHIATRIC DISORDERS
左岸公园
发明人：CECCARELLI, Simona, Maria,PINARD,
灵芝用途
Emmanuel,STALDER, Henri
申请号：EP04790408.1
鼻炎吃什么药效果好
申请日：20041014
公开号：EP1678177A1
公开日：
马格利酒
怎么安慰自己
20060712
专利内容由知识产权出版社提供
摘要：The invention relates to compounds of the general formula (I), wherein A-A is -CH2-CH2-, -CH2-CH2-CH2-, -CH2-0- or -0-CH2-; x is hydrogen or hydroxy; R1 is aryl or heteroaryl, unsubstituted or substituted by one or more substituents, lected from the group consisting of lower alkyl, lower alkoxy, halogen or trifluoromethyl; R2 is aryl or heteroaryl, unsubstituted or substituted by one or more substituents, lected from the group consisting of lower alkyl, lower alkoxy, halogen or trifluoromethyl, or is lower alkyl, -(CH2)n-c ycloalkyl, -(CH2)n-CF3, -(CH2)p-0-lower alkyl, -(CH2)1,2-phenyl, optionally substituted by halogen, lower alkyl, lower alkoxy or trifluoromethyl, or is -(CH2)p-NRR', wherein W and R' form together with the N-atom a heterocyclic ring, lected from the group consisting of piperidine, morpholine, thiomorpholine or 1, I-dioxo thiomorpholine; R3, R4 are independently from each other hydrogen, lower alkyl, phenyl or benzyl; R5 is hydrogen, lower alkyl or benzyl; R6 is hydrogen or lower alkyl; n is 0, 1 or 2; and p is 2 or 3; and to pharmaceutically acceptable acid addition salts thereof for the treatment of
psychos, pain, neurodegenerative disfunction in memory and learning, schizophrenia, dementia and other dias in which cognitive process are impaired, such as attention deficit disorders or Alzheimer's dia.
申请人：F.HOFFMANN-LA ROCHE AG
地址：Grenzacherstras 124 4070 Bal CH
国籍：CH
韩版风衣
代理机构：Poppe, Regina
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