专利名称：Conjugate having a cleavable linkage for u in a liposome
发明人：Samuel Zalipsky,Alberto A. Gabizon
说课大赛
申请号：US11202913
申请日：20050812
杨玉莹小说公开号：US20050271715A1
公开日：
20051208
专利内容由知识产权出版社提供
名师大讲堂摘要：Conjugates of a hydrophobic moiety, such as a lipid, linked through a cleavable dithiobenzyl linkage to a therapeutic agent are described. The dithiobenzyl linkage is susceptible to cleavage by mild thiolysis, resulting in relea of the therapeutic agent in its original form. The linkage is stable under nonreducing conditions. The conjugate can be incorporated into liposomes for administration in vivo and relea of the therapeutic agent in respon to endogeneous in vivo reducing conditions or in respon to administration of an exogeneous reducing agent.
斑蝶申请人：Samuel Zalipsky,Alberto A. Gabizon
地址：Redwood City CA US,Jerusalem IL
猪脚火锅
桂贤娣国籍：US,IL体育微课
更多信息请下载全文后查看
杨家将是真实历史吗
