Synthesis, biological evaluation, and docking stud

更新时间:2023-05-14 19:48:34 阅读: 评论:0

炒面怎么炒
出生的英语
Synthesis, biological evaluation, and docking studies of PAR2-AP-derived pudopeptides as inhibitors of kallikrein 5 and 6期刊名称: Biological Chemistry
作者: Severino, Beatrice,Fiorino, Ferdinando,Corvino, Angela,Caliendo,
中国古代神话读后感
Giuppe,Santagada, Vincenzo,Assis, Diego Magno,Oliveira, Juliana R.,Juliano, Luiz,Manganelli, Serena,Benfenati, Emilio,Frecente, Francesco,Perissutti,
幼师座右铭
Elisa,Juliano, Maria Aparecida
年份: 2015年
中国考古学期号: 第1期
关键词: human kallikrein 5;human kallikrein 6;inhibitor;molecular
modeling;rine protea
感冒英语怎么说摘要:A ries of protea activated receptor 2 activating peptide (PAR2-AP) derivatives (1–15) were 物质的量浓度计算公式
designed and synthesized. The obtained compounds were tested on a panel of human kallikreins (hKLK1, hKLK2, hKLK5, hKLK6, and hKLK7) and were found completely inactive toward hKLK1, hKLK2, and hKLK7. Aiming to investigate the mode of interaction between the most interesting compounds and the lected hKLKs, docking studies were performed. The described compounds distinguish the different human tissue kallikreins with compounds 1 and 5 as the best hKLK5 and hKLK6 inhibitors, respectively.
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