肠道巨噬细胞的功能异质性(综述)热心肠日报
Gut
面容憔悴
[IF:19.819]
Niche-specific functional heterogeneity of intestinal resident macrophages
核心人才肠道巨噬细胞的功能异质性
10.1136/gutjnl-2020-323121挂纸
金思雨2020-12-31, Article
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Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the respo
n to food antigens and bacteria that are able to penetrate the mucosal barrier. However, recent advances in single-cell RNA quencing technology have revealed that resident macrophages throughout the gut are functionally specialid to carry out specific roles in the niche they occupy, leading to an unprecedented understanding of the heterogeneity and potential biological functions of the cells. This review aims to integrate the novel findings with long-standing knowledge, to provide an updated overview on our understanding of macrophage function in the gastrointestinal tract and to speculate on the role of specialid subts in the context of homoeostasis and dia.
First Authors:
低盐饮食有利于预防什么疾病
Maria Francesca Viola
鲁迅外国语学校Correspondence Authors:景德镇旅游景点
Guy Boeckxstaens
高一数学上册
All Authors:
Maria Francesca Viola,Guy Boeckxstaens