弄明⽩了C18和ODS，那L1的⾊谱柱⼜是什么⿁？
上周的微问答中，我们提到 ODS柱，就是OctaDecyl Silane⼗⼋烷基硅烷柱，也叫C18柱。
除了 C18 和 ODS 这样的代号，资料中还会使⽤其它的代号，⽐如有同学就提出了这样的问
题：
Q
像这种L多少的柱⼦是什么填料呢？——@sunny
这种L开头的代号是美国药典的填料型号。
L代表Liquid Chromtography，所以，还有G开头的代号，那就表⽰⽓相系列的柱⼦啦。
在@sunny 同学的这份⽂件中，使⽤了L1、L3、L40、L41、L66。
其中L1 对应的是⼗⼋烷基键合多孔硅胶固定相，也就是最常⽤的C18柱。
L3对应的是多孔硅胶柱，⽤于正相模式或HILIC模式。
⽐较容易混淆的是L1和L2，似乎都是Octadecyl silane C18柱。
同学们猜猜看，他们的区别是什么呢？
欢迎给我们留⾔，答对的同学给你们送⼩礼物哦~
C18柱都有什么区别呢？
HILIC模式⼜是什么？
食品管理制度
最后，给⼤家附上L1-L62 型号的说明表，⽅便⼤家收藏和查找：
型号说明
L1 Octadecyl silane chemically bonded to porous
silica or ceramic.
L1⼗⼋烷基键合硅烷化学键合于多孔硅胶或陶瓷微
粒。
L2 Octadecyl silane chemically bonded to silica gel of
a controlled surface porosity that has been bonded
to a solid spherical core, 30 to 50 µm in diameter.
L2⼗⼋烷基键合硅烷化学键合于表⾯空隙率⼀定的键
合在紧密球核上的硅胶，粒径30-50u。
L3 Porous silica particles, 5 to 10 µm in diameter.
L3多孔硅胶颗粒，粒径5-10u。
L4 Silica gel of controlled surface porosity bonded to a
solid spherical core,30 to 50 µm in diameter.
L4表⾯空隙率⼀定的硅胶键合于紧密球核上，粒径30-
50u。
L5 Alumina of controlled surface porosity bonded to a
solid spherical core,30 to 50 µm in diameter.
L5表⾯空隙率⼀定的氧化铝键合于紧密球核上，粒径30-50u。
L6 Strong cation-exchange packing sulfonated fluorocarbon polymer coated on a solid spherical
core, 30 to 50 µm in diameter.
L6强阳离⼦交换填料：磺化氟代烃聚合物涂渍于紧密球核上，粒径30-50u。
L7 Octyl silane chemically bonded to totally porous silica particles, 1.5 to 10 µm in diameter.
L7⾟基硅烷化学键合于完全多孔硅胶担体，粒径10u。L8 An esntially monomolecular layer of
aminopropyl-silane chemically bonded to totally
porous silica gel support, 3 to 10 µm in diameter.
L8氨丙基硅烷单分⼦层化学键合于完全多孔硅胶担体，粒径10u。
L9 Irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic ation-
exchange coating, 3 to 10 µm in diameter.
L9 10u不规则的完全多孔硅胶具有化学键合的强酸性阳离⼦交换涂层。
L10 Nitrile groups chemically bonded to porous silica particles, 3 to 10 µm in diameter.
L10氰基团化学键合于多孔微粒硅，粒径3-10u。
L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter.
L11苯基化学键合于多孔微粒硅，粒径3-10u。
L12 Strong anion-exchange packing made by
chemically bonding a quaternary amine to a solid
silica spherical core, 30 to 50 µm in diameter
L12由四元胺化学键合于精密硅球核形成的强阴离⼦交换填料，粒径30-50u。
L13 Trimethylsilane chemically bonded to porous silica particles,3 to 10 µm in diameter.
L13三甲基硅烷化学键合于完全多孔硅胶，粒径3-10u。L14 Silica gel having a chemically bonded, strongly basic quaternary ammonium anion-exchange
coating, 5 to 10 µm in diameter.
L14具有强碱性四元胺阴离⼦交换涂层的10u硅胶化学键合相。
L15 Hexyl silane chemically bonded to totally porous silica particles,3 to 10 µm in diameter.
L15⼰基硅烷化学键合于完全多孔性微粒硅，粒径3-10u。
L16 Dimethyl silane chemically bonded to totally porous silica particles, 5 to 10 µm in diameter.
L16⼆甲基硅烷化学键合于完全多孔性微粒硅，粒径3-10u。
L17 Strong cation-exchange resin consisting of sulfonated cross-linked styrene-divinylbenzene
copolymer in the hydrogen form, 7 to 11 µm in
diameter.
L17由磺化的苯⼄烯-⼆⼄烯基苯交连共聚物组成的氢型阳离⼦交换树脂，粒径7-11u。
L18 Amino and cyano groups chemically bonded to
L18 Amino and cyano groups chemically bonded to porous silica particles,3 to 10 µm in diameter.
L18氨基和氰基化学键合于多孔微粒硅，粒径3-10u。L19 Strong cation-exchange resin consisting of
sulfonated cross-linked styrene-divinylbenzene
copolymer in the calcium form, 9 µm in diameter.
芬芳满堂
L19由磺化的苯⼄烯-⼆⼄烯基苯交连共聚物组成的钙型阳离⼦交换树脂，粒径7-11u。
L20 Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 µm in diameter.
L20⼆甲氧基丙烷基化学键合于多孔硅胶微粒，粒径5-10u。
L21 A rigid, spherical styrene-divinylbenzene
copolymer, 5 to 10 µm in diameter.
L21刚性球形苯⼄烯-⼆⼄烯基苯共聚物，粒径5-10u。L22 A cation exchange resin made of porous
polystyrene gel with sulfonic acid groups, about 10
µm in size.
L22由多孔聚苯⼄烯凝胶和磺酸基组成的阳离⼦交换树脂，粒径约为10u。
L23 An anion exchange resin made of porous
polymethacrylate or polyacrylate gel with quaternary
ammonium groups, about 10 µm in size.公务员法实施细则
L23由多孔聚甲基丙烯酸酯或聚丙烯酸酯凝胶及四元胺基组成的阴离⼦交换树脂，粒径约为10u。
L24 A mi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the
matrix surface, 32 to 63 µm in diameter.
L24由⼄烯基聚合物和基质表⾯的⽆数羟基组成的半刚性亲⽔硅胶，粒径32u-63u。
L25 Packing having the capacity to parate
compounds with a MW range from 100 to 5000
daltons (as determined by polyethylene oxide),
applied to neutral, anionic, and cationic water-
soluble polymers. A polymethacrylate resin
ba,crosslinked with poly-hydroxylated ether
(surface contained some residual carboxyl
functional groups) was found suitable.
L25能分离MW从100到5000Da化合物的填料（取决于聚环氧⼄烷），应⽤于中性、阴离⼦和阳离⼦的⽔溶
性聚合物。聚甲基丙烯酸酯作为树脂基质，与聚羟基
化醚（表⾯含⼀些残余羧基官能团）进⾏交连。
L26 Butyl silane chemically bonded to totally porous silica particles, 5 to 10 µm in diameter.
L26丁基硅烷化学键合全多孔硅胶微球固定相，即C4柱L27 Porous silica particles, 30 to 50 µm in diameter.
L28 A multifunctional support, which consists of a high purity, 100 , spherical silica substrate that has been
bonded with anionic (amine) functionality in
addition to a conventional reverd pha C8
functionality.
L29 Gamma alumina, reverd pha, low carbon percentage by weight, alumina-bad
polybutadiene spherical particles, 5 µm diameter
with a pore diameter of 80 .
L30 Ethyl silane chemically bonded to a totally porous silica particle, 3 to 10 µm in diameter.
L31 A strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5
九阳电压力锅µm macroporous particles having a pore size of
2000 Å and consisting of ethylvinylbenzene cross-
linked with 55 % divinyl benzene.
L32 A chiral ligand-exchange packing- L-proline copper complex covalently bonded to irregularly shaped
silica particles, 5 to 10 µm in diameter.
L33 Packing having the capacity to parate proteins of 4,000 to 400,000 daltons. It is spherical, silica-
bad and procesd to provide pH stability.
L34 Strong cation-exchange resin consisting of
sulfonated cross-linked styrene-divinylbenzene
copolymer in the lead form, about 9 µm in diameter. L35 A zirconium-stabilized spherical silica packing with
a hydrophilic (diol-type) molecular monolayer
bonded pha having a pore size of 150 .
L36 3,5-dinitrobenzoyl derivative of L-phenylglycine covalently bonded to 5 µm aminopropyl silica.
L37 Polymethacrylate gel packing having the capacity to parate proteins by molecular size over a range
of 2,000 to 40,000D.
不再错过你
L38 Methacrylate-bad size-exclusion packing for water-soluble samples.
L39 Hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin.
L40 Cellulo tris-3,5-dimethylphenylcarbamate coated porous silica particles,5 µm to 20 µm in dia
meter.
L40 Tris 3,5－⼆甲基苯基氨基甲酸酯纤维素涂覆多孔硅胶微球
L41 Immobilized á-acid glycoprotein on spherical silica particles, 5 µm in diameter.
L41球形硅胶表⾯固定α1酸糖蛋⽩固定相
L42 Octylsilane and octadecylsilane groups chemically bonded to porous silica particles,5 µm in diameter.
L43 Pentafluorophenyl groups chemically bonded to silica particles, 5 to 10 µm in diameter.
L44 A multifunctional support, which consists of a high purity, 60 , spherical silica substrate that has been
bonded with a cationic exchanger, sulfonic acid
functionality in addition to a conventional reverd
pha C8 functionality.
L45 Beta cyclodextrin bonded to porous silica particles,
5 to 10 µm in diameter.
L46 Polystyrene/divinylbenzene substrate
agglomerated with quaternary amine functionalized
latex beads, 10 µm in diameter.
L47 High capacity anion-exchange microporous substrate, fully functionalized with a trimethylamine
group, 8 µm in diameter.
L48 Sulfonated, cross-linked polystyrene with an outer
L48 Sulfonated, cross-linked polystyrene with an outer layer of submicron, porous,anion-exchange
microbeads, 15 µm in diameter.
L49 A reverd-pha packing made by coating a thin layer of polybutadiene on to spherical porous
zirconia particles, 3 to 10 µm in diameter.
L50 Multifunction resin with reverd-pha retention and strong anion-exchange functionalities. The
resin consists of ethylvinylbenzene, 55 % cross-
linked with divinylbenzene copolymer, 3 to 15 µm in
diameter, and a surface area of not less than 350
鼓励人的话语
m2/g, substrate is coated with quaternary
ammonium functionalized latex particles consisting
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of styrene cross-linked with divinylbenzene.
L51 Amylo tris-3,5-dimethylphenylcarbamate-coated, porous, spherical, silica particles,5 to 10 µm in
diameter.
L52 A strong cation exchange resin made of porous silica with sulfopropyl groups, 5 to 10 µm in
diameter.
L53 Weak cation-exchange resin consisting of
ethylvinylbenzene, 55 % cross-linked with
divinylbenzene copolymer, 3 to 15 µm diameter.
指南针制作
Substrate is surface grafted with carboxylic acid
and/or phosphoric acid functionalized monomers.
Capacity not less than 500 µm in diameter.
L54 A size exclusion medium made of covalent
bonding of dextran to highly cross-linked porous
agaro beads, about 13 µm in diameter.
L55 A strong cation exchange resin made of porous silica coated with polybutadiene-maleic acid
copolymer, about 5 µm in diameter.
L56 Isopropyl silane chemically bonded to totally porous silica particles, 3 to 10 µm in diameter.
L57 A chiral-recognition protein, ovomucoid, chemically bonded to silica particles, about 5 µm in diameter,
with a pore size of 120 angstroms.
L58 Strong cation-exchange resin consisting of
sulfonated cross-linked styrene- divinylbenzene
copolymer in the sodium form, about 7 to 11 µm
diameter.
L59 To parate proteins by molecular weight over the range of 10 to 500 kDa. Spherical 10 µm, silica-
bad, and procesd to provide hydrophilic
characteristics and pH stability.
L60 Spherical, porous silica gel, 3 to 10 µm in diameter, surface has been covalently modified with
palmitamidopropyl groups and endcapped.
L61 Hydroxide-lective, strong anion-exchange resin consisting of a highly cross-linked core of 13 µm
microporous particles, pore size less than 10 , and
consisting of ethylvinylbenzene cross-linked with
55 % divinylbenzene with a latex coating compod
of 85 nm diameter microbeads bonded with alkanol
quarternary ammonium ions (6 %).
L62 C30 silane bonded pha on a fully porous
L62 C30 silane bonded pha on a fully porous spherical silica
