生理盐水在头孢类抗生素过敏试验前皮肤擦拭中的应用效果
作者：高梦徽 白晓静 马莉
来源：《中国医药导报》2019年第05期
[摘要] 目的 探讨生理盐水在头孢类抗生素过敏试验前皮肤擦拭中的应用效果。 方法 选取2016年9月～2017年3月四川省骨科医院下肢科收治且行头孢类抗生素过敏试验的500例患者，采用随机数字表法将其分为实验组和对照组，每组250例。实验组头孢类抗生素过敏试验前使用生理盐水进行清洁;对照组直接使用75%的酒精进行消毒。比较两组患者的头孢类抗生素过敏试效果及细菌学检测结果。 结果 实验组假阳性率明显低于对照组，差异有统计学意义（P < 0.05）。两组患者均无细菌检测不合格者，无菌合格率均为100.00%。 结论 生理盐水用于头孢类抗生素过敏试验的皮肤清洁，能有效降低头孢类抗生素过敏试验假阳性发生率。
[关键词] 生理盐水;头孢类抗生素;过敏试验;皮肤清洁
[中图分类号] R472; ; ; ; ; [文献标识码] A; ; ; ; ; [文章编号] 1673-7210（2019）02（b）-0159-04
[Abstract] Objective To investigate the effect of normal saline on skin wiping before cephalosporin antibiotic allergy test. Methods A total of 500 patients who underwent cephalosporin antibiotic allergy test in the Department of Lower Extremities of Sichuan Provincial Orthopaedic Hospital from September 2016 to March 2017 were randomly divided into experimental group and control group， with 250 cas in each group. The experimental group was cleaned with physiological saline before the cephalosporin antibiotic allergy test; the control group was directly disinfected with 75% alcohol. The cephalosporin antibiotic allergy test results and bacteriological test results of the two groups of patients were compared. Results The fal positive rate of the experimental group was significantly lower than that of the control group， and the difference was statistically significant （P < 0.05）. There were no bacterial test failures in both groups， and the sterility pass rate was 100.00%. Conclusion The u of saline for skin cleansing in cephalosporin antibiotic allergy tests can effectively reduce the incidence of fal positives in cephalosporin allergy tests.
