Idiopathic Anaphylaxis and Histamine Intolerance 期刊名称： Pediatric Allergy & Immunology Official Publication of the European Society of Pediatric Allergy & Immunology
作者： Ivkovic-Jurekovic, Irena
年份： 2015年
期号： 第7期
关键词： Anaphylaxis;Idiopathic;histamine intolerance
摘要：Notable increa of pediatric patients with idiopathic anaphylaxis (IA) has been noted in recent years. IA is a potentially life-threatening dia caud by an unknown trigger and it must be recognid and treated in a way that prevents fatal outcome. There have been no previous reports of IA with histamine intolerance (HI) in a pediatric patient. Possible connection of HI with IA needs further investigation. Positive autologous rum skin test (ASST) in our patients with IA yet with no proof of circulating auto antibodies against IgE and against subunit of the high-affinity IgE receptor suggests ot
her possible autoantibodies causing autoreactivity. Thus, autoimmunity could be another, up to now not sufficiently investigated cau of IA.
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