GeneBank序列注释说明
GeneBank格式的序列中，有一些注释很难弄明白它的意思，通过搜索，终于找到了其原始的解释说明。
现以NM_005715为一个简单的例子（##后面为说明）。
LOCUS NM_005715 4396 bp mRNA linear PRI 27-JUN-2012 ##说明accession num、序列长度和最后更新日期
DEFINITION Homo sapiens uronyl-2-sulfotransfera (UST), mRNA. ##序列所在基因功能描述
ACCESSION NM_005715 ##accession num
VERSION NM_005715.2 GI:194578911 ##accession版本号和所在基因GI号
KEYWORDS .
SOURCE Homo sapiens (human) ##序列来源，即序列所在物种
ORGANISM Homo sapiens ##序列物种生物学分类
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bas 1 to 4396) ##参考文献序号
AUTHORS Uher,R., Perroud,N., Ng,M.Y., Haur,J., Henigsberg,N., Maier,W., ##参考文献作者
Mors,O., Placentino,A., Rietschel,M., Souery,D., Zagar,T.,
Czerski,P.M., Jerman,B., Larn,E.R., Schulze,T.G., Zobel,A.,
Cohen-Woods,S., Pirlo,K., Butler,A.W., Muglia,P., Barnes,M.R.,
Lathrop,M., Farmer,A., Breen,G., Aitchison,K.J., Craig,I.,
Lewis,C.M. and McGuffin,P.
TITLE Genome-wide pharmacogenetics of antidepressant respon in the ##参考文献标题
GENDEP project
JOURNAL Am J Psychiatry 167 (5), 555-564 (2010) ##参考文献发表的杂志
PUBMED 20360315 ##在pubmed数据库中序号
REMARK GeneRIF: Clinical trial and genome-wide association study of
gene-dia association, gene-environment interaction, and
pharmacogenomic / toxicogenomic. (HuGE Navigator)
REFERENCE 2 (bas 1 to 4396)
AUTHORS Trynka,G., Zhernakova,A., Romanos,J., Franke,L., Hunt,K.A.,
Turner,G., Bruinenberg,M., Heap,G.A., Platteel,M., Ryan,A.W., de
Kovel,C., Holmes,G.K., Howdle,P.D., Walters,J.R., Sanders,D.S.,
Mulder,C.J., Mearin,M.L., Verbeek,W.H., Trimble,V., Stevens,F.M.,
Kelleher,D., Barisani,D., Bardella,M.T., McManus,R., van Heel,D.A.
and Wijmenga,C.
TITLE Coeliac dia-associated risk variants in TNFAIP3 and REL
implicate altered NF-kappaB signalling
JOURNAL Gut 58 (8), 1078-1083 (2009)
PUBMED 19240061
REMARK GeneRIF: Obrvational study of gene-dia association. (HuGE
Navigator)
REFERENCE 3 (bas 1 to 4396)
AUTHORS Xu,D., Song,D., Pedern,L.C. and Liu,J.
TITLE Mutational study of heparan sulfate 2-O-sulfotransfera and
chondroitin sulfate 2-O-sulfotransfera
JOURNAL J. Biol. Chem. 282 (11), 8356-8367 (2007)
PUBMED 17227754
REMARK GeneRIF: analysis of differences and similarities various residues
play in the biological roles of the HS-2OST and CS-2OST enzymes
REFERENCE 4 (bas 1 to 4396)
AUTHORS Ohtake,S., Kimata,K. and Habuchi,O.
TITLE Recognition of sulfation pattern of chondroitin sulfate by uronosyl
2-O-sulfotransfera
JOURNAL J. Biol. Chem. 280 (47), 39115-39123 (2005)
PUBMED 16192264
REMARK GeneRIF: 2OST transfers sulfate preferentially to the GlcA residue
located in a unique quence, -GalNAc(4SO(4))-GlcA-GalNAc(6SO(4))-.
REFERENCE 5 (bas 1 to 4396)
AUTHORS Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
…………
TITLE The DNA quence and analysis of human chromosome 6
JOURNAL Nature 425 (6960), 805-811 (2003)
PUBMED 14574404
REFERENCE 6 (bas 1 to 4396)
AUTHORS Kobayashi,M., Sugumaran,G., Liu,J., Shworak,N.W., Silbert,J.E. and
Ronberg,R.D.
TITLE Molecular cloning and characterization of a human uronyl
2-sulfotransfera that sulfates iduronyl and glucuronyl residues
in dermatan/chondroitin sulfate
JOURNAL J. Biol. Chem. 274 (15), 10474-10480 (1999)
PUBMED 10187838
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference quence was derived from
AI570697.1, DB496757.1, BC093668.1, AB020316.1 and CA842761.1.
