STATE OF CALIFORNIA
ENVIRONMENTAL PROTECTION AGENCY
OFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT
SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986 CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITY
FEBRUARY 8, 2013
The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revi and republish at least once per year the list of chemicals known to the State to cau cancer or reproductive toxicity. The identification number indicated in the following list is the Chemical Abstracts Service (CAS) Registry Number. No CAS number is given when veral substances are prented as a single listing. The date refers to the initial appearance of the chemical on the list. For easy reference, chemicals which are shown underlined are newly added. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subquently been removed.
Chemical Type of Toxicity CAS No. Date Listed
A-alpha-C (2-Amino-9H-pyrido cancer 26148-68-5 January 1, 1990
[2,3-b]indole)
Acetaldehyde cancer 75-07-0 April 1, 1988 Acetamide cancer 60-35-5 January 1, 1990 Acetazolamide developmental 59-66-5 August 20, 1999 Acetochlor cancer 34256-82-1 January 1, 1989 Acetohydroxamic acid developmental 546-88-3 April 1, 1990
骂大街2-Acetylaminofluorene cancer 53-96-3 July 1, 1987 Acifluorfen sodium cancer 62476-59-9 January 1, 1990 Acrylamide cancer 79-06-1 January 1, 1990 Acrylamide developmental, male 79-06-1 February 25, 2011 Acrylonitrile cancer 107-13-1 July 1, 1987 Actinomycin D cancer 50-76-0 October 1, 1989
developmental October 1, 1992 AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)] cancer 3688-53-7 July 1, 1987
acrylamide
Aflatoxins cancer --- January 1, 1988 Alachlor cancer 15972-60-8 January 1, 1989 Alcoholic beverages, when cancer --- July 1, 1988
associated with alcohol abu
Aldrin cancer 309-00-2 July 1, 1988
All-trans retinoic acid developmental 302-79-4 January 1, 1989 Allyl chloride cancer107-05-1January 1, 1990 Delisted October 29, 1999
Alprazolam developmental 28981-97-7 July 1, 1990 Altretamine developmental, male 645-05-6 August 20, 1999 Amantadine hydrochloride developmental 665-66-7 February 27, 2001 Amikacin sulfate developmental 39831-55-5 July 1, 1990
2-Aminoanthraquinone cancer 117-79-3 October 1, 1989
p-Aminoazobenzene cancer 60-09-3 January 1, 1990
o-Aminoazotoluene cancer 97-56-3 July 1, 1987
4-Aminobiphenyl (4-amino- cancer 92-67-1 February 27, 1987 diphenyl)
1-Amino-2,4-dibromo- cancer 81-49-2 August 26, 1997
anthraquinone
3-Amino-9-ethylcarbazole cancer 6109-97-3 July 1, 1989
hydrochloride
2-Aminofluorene cancer 153-78-6 January 29, 1999 Aminoglutethimide developmental 125-84-8 July 1, 1990 Aminoglycosides developmental --- October 1, 1992
1-Amino-2-methylanthraquinone cancer 82-28-0 October 1, 1989
2-Amino-5-(5-nitro-2-furyl)-1,3,4- cancer 712-68-5 July 1, 1987
thiadiazole
粉扑多久洗一次4-Amino-2-nitrophenol cancer 119-34-6 January 29, 1999 Aminopterin developmental, female 54-62-6 July 1, 1987 Amiodarone hydrochloride developmental, female, 19774-82-4 August 26, 1997
male
Amitraz developmental 33089-61-1 March 30, 1999 Amitrole cancer 61-82-5 July 1, 1987 Amoxapin
e developmental 14028-44-5 May 15, 1998 Amsacrine cancer 51264-14-3 August 7, 2009
tert-Amyl methyl ether developmental 994-05-8 December 18, 2009 Anabolic steroids female, male --- April 1, 1990 Analgesic mixtures containing cancer --- February 27, 1987 phenacetin
Androstenedione cancer 27208-37-3 May 3, 2011 Angiotensin converting enzyme developmental --- October 1, 1992
(ACE) inhibitors
Aniline cancer 62-53-3 January 1, 1990 Aniline hydrochloride cancer 142-04-1 May 15, 1998
o-Anisidine cancer 90-04-0 July 1, 1987
o-Anisidine hydrochloride cancer 134-29-2 July 1, 1987 Anisindione developmental 117-37-3 October 1, 1992 Anthraquinone cancer 84-65-1 September 28, 2007 Antimony oxide (Antimony trioxide) cancer 1309-64-4 October 1, 1990 Aramite cancer 140-57-8 July 1, 1987
Areca nut cancer --- February 3, 2006 Aristolochic acids cancer --- July 9, 2004 Arnic (inorganic arnic cancer -- February 27, 1987 compounds)
Arnic (inorganic oxides) developmental --- May 1, 1997 Asbestos cancer 1332-21-4 February 27, 1987 Aspirin (NOTE: It is especially developmental, female 50-78-2 July 1, 1990
important not to u aspirin
during the last three months of
pregnancy, unless specifically
高血压的健康指导directed to do so by a physician
becau it may cau problems
in the unborn child or
complications during delivery.)
Atenolol developmental 29122-68-7 August 26, 1997 Auramine cancer 492-80-8 July 1, 1987 Auranofin developmental 34031-32-8 January 29, 1999
Avermectin B1 (Abamectin) developmental 71751-41-2 December 3, 2010 Azacitidine cancer 320-6
7-2 January 1, 1992 Azarine cancer 115-02-6 July 1, 1987 Azathioprine cancer 446-86-6 February 27, 1987 Azathioprine developmental 446-86-6 September 1, 1996 Azobenzene cancer 103-33-3 January 1, 1990
Barbiturates developmental --- October 1, 1992 Beclomethasone dipropionate developmental 5534-09-8 May 15, 1998 Benomyl developmental, male 17804-35-2 July 1, 1991 Benthiavalicarb-isopropyl cancer 177406-68-7 July 1, 2008
Benz[a]anthracene cancer 56-55-3 July 1, 1987 Benzene cancer 71-43-2 February 27, 1987 Benzene developmental, male 71-43-2 December 26, 1997 Benzidine [and its salts] cancer 92-87-5 February 27, 1987 Benzidine-bad dyes cancer --- October 1, 1992 Benzodiazepines developmental --- October 1, 1992 Benzo[b]fluoranthene cancer 205-99-2 July 1, 1987 Benzo[j]fluoranthene cancer 205-82-3 July 1, 1987 Benzo[k]fluoranthene cancer 207-08-9 July 1, 1987 Benzofuran cancer 271-89-6 October 1, 1990 Benzophenone cancer 119-61-9 June 22, 2012 Benzo[a]pyrene cancer 50-32-8 July 1, 1987 Benzotrichloride cancer 98-07-7 July 1, 1987 Benzphetamine hydrochloride developmental 5411-22-3 April 1, 1990 Benzyl chloride cancer 100-44-7 January 1, 1990 Benzyl violet 4B cancer 1694-09-3 July 1, 1987 Beryllium and beryllium compounds cancer --- October 1, 1987 Betel quid with tobacco cancer --- January 1, 1990 Betel quid
without tobacco cancer --- February 3, 2006 2,2-Bis(bromomethyl)-1,3- cancer 3296-90-0 May 1, 1996
propanediol
Bis(2-chloroethyl)ether cancer 111-44-4 April 1, 1988
N,N-Bis(2-chloroethyl)-2- cancer 494-03-1 February 27, 1987 naphthylamine (Chlornapazine)
Bischloroethyl nitrosourea (BCNU) cancer 154-93-8 July 1, 1987
(Carmustine)
Bischloroethyl nitrosourea (BCNU) developmental 154-93-8 July 1, 1990
(Carmustine)
虽然却造句
Bis(chloromethyl)ether cancer 542-88-1 February 27, 1987 Bis(2-chloro-1-methylethyl)ether, cancer --- October 29, 1999 technical grade
中国梦的提出Bitumens, extracts of steam-refined cancer --- January 1, 1990
and air refined
Bracken fern cancer --- January 1, 1990 Bromacil lithium salt developmental 53404-19-6 May 18, 1999 Bromacil lithium salt male 53404-19-6 January 17, 2003 Bromate cancer 15541-45-4 May 31, 2002 Bromochloroacetic acid cancer 5589-96-8 April 6, 2010 Bromodichloromethane cancer 75-27-4 January 1, 1990 Bromoethane cancer 74-96-4 December 22, 2000 Bromoform cancer 75-25-2 April 1, 1991
1-Bromopropane (1-BP) developmental, female, 106-94-5 December 7, 2004
male
2-Bromopropane (2-BP) female, male 75-26-3 May 31, 2005 Bromoxynil
developmental 1689-84-5 October 1, 1990 Bromoxynil octanoate developmental 1689-99-2 May 18, 1999 Butabarbital sodium developmental 143-81-7 October 1, 1992 1,3-Butadiene cancer
106-99-0 April 1, 1988 1,3-Butadiene developmental, female, 106-99-0 April 16, 2004
male
西兰花的营养价值1,4-Butanediol dimethanesulfonate cancer 55-98-1 February 27, 1987 (Busulfan)
沈煜伦
1,4-Butanediol dimethanesulfonate developmental 55-98-1 January 1, 1989 (Busulfan)
Butylated hydroxyanisole cancer
25013-16-5 January 1, 1990 Butyl benzyl phthalate (BBP) developmental 85-68-7 December 2, 2005 n-Butyl glycidyl ether male 2426-08-6 August 7, 2009 beta-Butyrolactone cancer 3068-88-0 July 1, 1987
Cacodylic acid cancer
75-60-5 May 1, 1996 Cadmium
developmental, male --- May 1, 1997 Cadmium and cadmium cancer --- October 1, 1987 compounds
Caffeic acid cancer 331-39-5 October 1, 1994 Captafol cancer 2425-06-1 October 1, 1988 Captan
cancer
133-06-2 January 1, 1990 Carbamazepine developmental 298-46-4 January 29, 1999 Carbaryl cancer
63-25-2 February 5, 2010 Carbaryl developmental, male 63-25-2 August 7, 2009 Carbazole
cancer 86-74-8 May 1, 1996
Carbon black (airborne, unbound cancer 1333-86-4 February 21, 2003 particles of respirable size)
Carbon disulfide developmental, female, 75-15-0 July 1, 1989
male
Carbon monoxide developmental 630-08-0 July 1, 1989 Carbon tetrachloride cancer 56-23-5 October 1, 1987 Carbon-black extracts cancer
---
January 1, 1990 Carboplatin
developmental 41575-94-4 July 1, 1990
N-Carboxymethyl-N-nitrosourea cancer 60391-92-6 January 25, 2002 Catechol
cancer 120-80-9 July 15, 2003 Ceramic fibers (airborne particles cancer --- July 1, 1990 of respirable size)
Certain combined chemotherapy cancer --- February 27, 1987 for lymphomas
Chenodiol developmental 474-25-9 April 1, 1990
Chlorambucil cancer
305-03-3 February 27, 1987 Chlorambucil developmental 305-03-3 January 1, 1989 Chloramphenicol
Delisted January 4, 2013 cancer 56-75-7 October 1, 1989 Chlorcyclizine hydrochloride developmental 1620-21-9 July 1, 1987 Chlordane
cancer
57-74-9
July 1, 1988
Chlordecone (Kepone) cancer
143-50-0 January 1, 1988 Chlordecone (Kepone) developmental 143-50-0 January 1, 1989 Chlordiazepoxide
developmental 58-25-3 January 1, 1992 Chlordiazepoxide hydrochloride developmental 438-41-5 January 1, 1992 Chlordimeform cancer 6164-98-3 January 1, 1989 Chlorendic acid
cancer 115-28-6 July 1, 1989 Chlorinated paraffins (Average cancer 108171-26-2 July 1, 1989 chain length, C12; approximately 60 percent chlorine by weight)
扑朔迷离什么意思p -Chloroaniline
cancer 106-47-8 October 1, 1994 p -Chloroaniline hydrochloride cancer 20265-96-7 May 15, 1998 Chlorodibromomethane cancer 124-48-1 January 1, 1990 Delisted October 29, 1999
Chloroethane (Ethyl chloride) cancer 75-00-3 July 1, 1990 1-(2-Chloroethyl)-3-cyclohexyl- cancer 13010-47-4 January 1, 1988 1-nitrosourea (CCNU) (Lomustine)
1-(2-Chloroethyl)-3-cyclohexyl- developmental 13010-47-4 July 1, 1990 1-nitrosourea (CCNU) Lomustine)
1-(2-Chloroethyl)-3-(4-methyl- cancer 13909-09-6 October 1, 1988 cyclohexyl) -1-nitrosourea (Methyl-CCNU)
Chloroform cancer
67-66-3 October 1, 1987 Chloroform
developmental 67-66-3 August 7, 2009 Chloromethyl methyl ether cancer 107-30-2 February 27, 1987 (technical grade)
3-Chloro-2-methylpropene cancer 563-47-3 July 1, 1989
1-Chloro-4-nitrobenzene
cancer 100-00-5 October 29, 1999 4-Chloro-o -phenylenediamine cancer 95-83-0 January 1, 1988 Chloroprene
cancer 126-99-8 June 2, 2000 2-Chloropropionic acid male 598-78-7 August 7, 2009 Chlorothalonil
cancer 1897-45-6 January 1, 1989 p -Chloro-o -toluidine
cancer 95-69-2 January 1, 1990 p-Chloro-o -toluidine, strong acid cancer --- May 15, 1998 salts of
5-Chloro-o -toluidine and cancer --- October 24, 1997 its strong acid salts
Chlorotrianine cancer 569-57-3 September 1, 1996 Chlorozotocin cancer
54749-90-5 January 1, 1992 Chlorsulfuron developmental, female, 64902-72-3 May 14, 1999
male
Chromium (hexavalent compounds) cancer
--- February 27, 1987 Chromium (hexavalent compounds) developmental, female, male ---
December 19, 2008 Chryne
cancer 218-01-9 January 1, 1990 C.I. Acid Red 114 cancer 6459-94-5 July 1, 1992 C.I. Basic Red 9 cancer 569-61-9 July 1, 1989 monohydrochloride
C.I. Direct Blue 15 cancer 2429-74-5 August 26, 1997 C.I. Direct Blue 218 cancer 28407-37-6 August 26, 1997 C.I. Disper Yellow 3 cancer 2832-40-8 February 8, 2013 C.I. Solvent Yellow 14
cancer 842-07-9 May 15, 1998 Ciclosporin (Cyclosporin A; cancer 59865-13-3 January 1, 1992 Cyclosporine)
79217-60-0
