Synthesis and Characterization of Silver Nanoparticle Modified 3-Aminophenol Resin Microspheres with Application for Determination of Carcinoembryonic Antigens by Surface-Enhanced
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期刊名称: Analytical Letters
作者: Tao, Lin,Lu, Wenbo,Wang, Man,Wang, Ying,Dong, Jian,Qian, Weiping
年份: 2015年海底简笔画>苹果手机怎么查询是不是正品
期号: 第14期
吹泡泡舞蹈关键词: Carcinoembryonic antigen;Immunoassay;Phenolic resin洋菠菜
microspheres;Surface-enhanced Raman scattering
摘要:Uniform phenolic resin microspheres were prepared by the polycondensation of 3-aminophenol and formaldehyde. On the surface of the 3-aminophenol resin microspheres, silver nanoparticles were
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synthesized in situ and immobilized by simple heating. The composite was employed as a substrate for surface-enhanced Raman scattering (SERS). The SERS enhancement factor was evaluated using 4-mercaptobenzoic acid and Nile blue A as signal molecules. A highly nsitive SERS immunoassay that combined labeled antibody conjugated
silver nanoparticle modified 3-aminophenol resin microspheres and coating antibody conjugated magnetic nanoparticles was fabricated to determine carcinoembryonic antigen. A linear relationship was obtained between the Raman intensity and the concentration of carcinoembryonic antigen. The limit of detection was 1.2 产品策划
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