元朝专利名称:A MODIFIED GALECTIN-2 AND USES THEREOF
发明人:HE, LIZHONG,WANG, HUI,MIDDELBERG, ANTON, P., J.
申请号:EP09749330阳春面的做法大全
申请日:20090518
军旗的规则
最难做的饭公开号:EP2291396A4欧式图片大全
公开日:
成天龙
20120125
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摘要:An isolated modified galectin-2 protein comprising a mutation and/or modification which improves one or more properties of said isolated modified galectin-2 are provided. More particularly, the mutation of galectin-2 is substitution of cysteine (57), preferably with a methionine residue. Modification of an isolated galectin-2 includes a modification of cysteine (75). Modification includes chemical modification by PEGylation or alkylation. Also provided are isolated nucleic acid, genetic constructs comprising said isolated nucleic acids, antibodies, compositions and methods of modulating an immune respon that may be uful in therapeutic and/or prophylactic treatment of dia, disorders or considers which involve an immune respon is mediated by one or more cytokines or other soluble immunomodulators and/or the immune respon is mediated by one or more cells of the immune system.
申请人:THE UNIVERSITY OF QUEENSLAND
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