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Prior Food Allergic Individuals Could Be at Risk of Developing Eosinophilic Esophagitis to硬盘整数分区
the Same Food
SAN DIEGO, CA – According to a study prented at the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI), people who have outgrown a food allergy might be at risk of developing another condition—called eosinophilic esophagitis (EoE)—to the same food.
“EoE is characterized by the prence of large numbers of white blood cells called eosinophils in the tissue of the esophagus, which caus inflammation or swelling of the esophagus,” explained Jonathan M. Spergel, MD, PhD, FAAAAI, one of the study authors. “Foods like dairy products, egg, soy and wheat are main caus of EoE.”
In their rearch, Dr. Spergel and colleagues at Children’s Hospital of Philadelphia t out to examine the frequency of food allergy in patients with EoE.运动的好处
The sample studied was comprid of 1,025 children with EoE who were patients at Children’s Hospital of Philadelphia between 2000 and 2012. In 425 of tho children, a specific food had been identified as the culprit. A food was considered to cau EoE if removing it from the diet stopped symptoms or reintroducing it into the diet caud symptoms to reoccur.
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Among the 425 children with EoE who had a culprit food identified, the most common EoE triggers were milk, egg, wheat and soy. However, what was most interesting to rearchers was that a group of 17 patients had developed EoE to a food after they outgrew an allergy to that same food.
Milk, egg, wheat and soy were still the most common EoE triggers in this subgroup and 94% of the patients had atopic dia. The investigators noted that two subjects even had normal biopsies of the esophagus at the time when they had a food allergy. Then after they outgrew that
food allergy, they developed EoE to the same food coinciding with the reintroduction of that food into their diet.
“What we’re really eing is that the paths of development for EoE and food allergy are distinct from each other, and we still need to learn more,” said Dr. Spergel. “The most interesting finding though is that we’re now eing that people who outgrow a food allergy to a specific food may be at risk of developing EoE to the same food.”
More information on EoE and food allergy is available from the AAAAI website.微信通讯录
The AAAAI reprents allergists, asthma specialists, clinical immunologists, allied health professiona
ls and others with a special interest in the rearch and treatment of allergic dia. Established in 1943, the AAAAI has more than 6,700 members in the United States, Canada and 60 other countries.
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Editor's notes:
•This study was prented during the 2014 Annual Meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI) on February 28-March 4 in San Diego.
谱写新篇章However, they do not necessarily reflect the policies or the opinions of the AAAAI.
• A link to all abstracts prented at the Annual Meeting is available at
annualmeeting.aaaai
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