adventure
告别薇安Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells墨兰多久浇一次水>温哥华留学
期刊名称： Autophagy
作者： Carreira, Raquel S.,Lee, Youngil,Ghochani, Mariam, Gustafsson, ?sa
B.,Gottlieb, Roberta A.
形容刻苦学习的成语
年份： 2010年
期号： 第4期
关键词： autophagy; cardiac myocyte; cyclophilin D; mitochondrial permeability
图片轮播尺寸
transition; mitophagy
摘要：Autophagy is a highly regulated intracellular degradation process by which cells remove cytosolic long-lived proteins and damaged organelles. The mitochondrial permeability transition (MPT) results in mitochondrial depolarization and incread reactive oxygen species production, which can tri
腐乳空心菜gger autophagy. Therefore, we hypothesized that the MPT may have a role in signaling autophagy in cardiac cells. Mitochondrial membrane potential was lower in HL-1 cells subjected
to starvation compared to cells maintained in full medium. Mitochondrial membrane potential was prerved in starved cells treated with cyclosporin A (CsA), suggesting the MPT pore is associated with starvation-induced depolarization. Starvation-induced autophagy in HL-1 cells, neonatal rat cardiomyocytes and adult mou cardiomyocytes was inhibited by CsA.
内容由中国教育图书进出口有限公司引进有关数学的名言
