专利名称：COMPOSITIONS AND METHODS TO
PROTECT CELLS BY BLOCKING ENTRY OF
PATHOGEN PROTEINS
发明人：TYLER, Brett,KALE, Shiv,ANTIGNANI,
Vincenzo
申请号：US2010/056351
申请日：20101111
公开号：WO2011/060144A2
公开日：幸福就是
无锡市灵山景区
鱼掉鳞怎么回事20110519古诗词起名
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摘要：Pathogenic effector proteins include one or more virulence motifs of amino acid
connsus quence BXZ, where B = RK or H; X = any amino acid or is abnt; Z = L, M, I, W, Y or F) which bind to target polar lipids on a host (plant or animal) cell as a prerequisite for translocation of the pathogenic effector proteins into the cell. Translocation is prevented by binding blocking compounds to one or more motifs of the effector protein or to the lipid Iigands of the host cell. The blocking compounds include synthetic or naturally occurring polypeptides which bind the polar lipids or the motifs, various polar lipids, the hydrophilic head-groups of polar lipids, etc. Suitable blocking compounds can be identified by assays demonstrating binding to the motifs or to the target polar lipids.
申请人：VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.,TYLER, Brett,KALE,
写给女朋友的一封信Shiv,ANTIGNANI, Vincenzo
地址：24060 US,24060 US,22033 US,24060-5544 US
国籍：US,US,US,US
代理人：CHRISTOFFERSON, Clyde, R. et al.
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