道歉的句子给爱人
专利名称：Computer implemented system for protein
and drug target design utilizing quantified
正月十六日
父亲的故事stability and flexibility relationships to
control function
发明人：Donald J Jacobs,Dennis R. Livesay
申请号：US12344512
清明节的诗句申请日：20081227
公开号：US08374828B1
愚公移山英语作文
公开日：
俞敏洪励志故事20130212
专利内容由知识产权出版社提供
专利附图：
jaca摘要：The computerized method, software, and product of this invention implements拉皮的做法
a process for computationally designing proteins and/or associated molecular targets with desired quantitative stability/flexibility relationships (QSFR). QSFR is an innovative, high dimensional metric calculated using an improved Distance Constraint Model (DCM). This invention includes three distinct aspects: (i.) utilizing QSFR in computational molecular design of protein quences, or variations of molecular structures, to have specific stability and flexibility relationships deemed important for biochemical function for specified thermodynamic and solvent conditions; (ii.) utilizing QSFR to optimize thermodynamic and/or solvent conditions necessary for a specified molecular system to exhibit protein function characteristics, such as improved catalytic efficiency; and (iii.) utilizing QSFR to computationally screen or design small molecules and/or design its putative receptor so as to exhibit a desired affect on protein function.
申请人：Donald J Jacobs,Dennis R. Livesay
地址：Charlotte NC US,Charlotte NC US
国籍：US,US
代理机构：Summa, Additon & Ashe, P.A.
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