情感脆弱
24节气表口诀Identification and characterization of novel infection associated transcripts in macrophages 期刊名称: RNA Biology培训方案
中国人寿养老保险股份有限公司作者: Prabhakar Arumugam,Rakesh Lodha,vivek Rao如何安全用电
年份: 2021年
期号: 第S2期
辞的组词关键词: Non coding transcript;TLR4;bacterial infection;THP1
白雪公主童话故事
摘要:Regulated expression of genes in respon to internal and external stimuli is primarily responsible for the enormous plasticity and robustness of biological systems. Recent studies have elucidated complex regulatory non protein coding transcript (lncRNA) circuits in coordinated respon of immune cells. By analysis of lncRNA expression profiles of macrophages in respon to Mtb infection, we identified novel highly expresd transcripts, unique in encompassing one functional protein coding transcript- CMPK2 and a previously identified type I IFN responsive lncRNA- NRIR. Whil
e the RNA are induced by virulent Mtb early, the complete abnce of expression in non-viable Mtb infected cells coupled to a more protracted expression profile in the ca of BCG suggest an important role in macrophage respon to mycobacteria. Moreover,
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