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小学时代Non-coding transcript variants of protein-coding genes – what are they good for?
期刊名称： RNA Biology
作者： Dhamija Sonam, Menon Manoj B.
年份： 2018年
关键词： cncRNAs;lncRNAs;translation;splicing;smORF;non-coding
RNA;ceRNA;circRNA
肾结石怎么检查>腊肠的做法大全>爱丁堡动物园摘要：The total number of protein-coding genes in the human genome is not significantly higher than tho in much simpler eukaryotes, despite a general increa in genome size proportionate to the organismal complexity. The large non-coding transcriptome and extensive differential splicing, are increasingly being accepted as the factors contributing to the complex mammalian physiology and architecture. Recent studies reveal additional layers of functional complexity: some long non-coding RNAs have been re-defined as micropeptide or microprotein encoding transcripts, and in turn some pro
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tein-coding RNAs are bifunctional and display also non-coding functions. Moreover, veral protein-coding genes express long non-coding RNA splice-forms and generate circular RNAs in addition to their canonical mRNA transcripts, revoking the strict
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