蕈样肉芽肿我有一双隐形的翅膀孕16~28周胎儿脐血β-地中海贫血基因及其血红蛋白电泳＼红细胞参数变异分析
英语月考总结 目的：探讨红细胞参数和毛细管血红蛋白电泳及β-地中海贫血基因检测在产前诊断β-地中海贫血中的互补作用。方法：210 例孕16～28周胎儿脐血标本根据β-地中海贫血基因型测定结果分为4 组，对4 组血常规结果中的平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）、平均红细胞血红蛋白浓度（MCHC）及血红蛋白A（HbA%）、等多参数进行统计分析。结果：对照组MCV、MCH、MCHC与其他各组结果对比差异无统计学意义（P>0.05）；但HbA（%）在其他组间的结果均低于对照组，差异有统计学意义（P＜0.05）。结论：孕16～28周胎儿脐血MCV、MCH及MCHC检测对β-地中海贫血的产前诊断价值不大，而脐血毛细管血红蛋白电泳及β-地中海贫血基因联合检测则有很好的互补作用。
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[Abstract] Objective: To study the red blood cell parameters and capillary electrophoresis and β-hemoglobin gene to detect anemia in the prenatal diagnosis of β thalasmia in the complementary role. Methods: 210 pregnant and 16 to 28 weeks of fetal cord blood samples according to determination of β-thalasmia genotypes were divided into 4 groups, 4 groups of blood results mean corpuscular volume (MCV), mean corpuscular hemoglobin (合理利用时间
傣族美食MCH), mean corpuscular hemoglobin concentration (MCHC) and hemoglobin A (HbA%), and other parameters were analyzed. Results: In Group MCV, MCH, MCHC compared with results of other groups no significant difference (P>0.05); but HbA (%) results in the other groups were lower than the control group, the difference was statistically significant (P＜0.05). Conclusion: 16-28 weeks pregnant fetal cord blood MCV, MCH and MCHC detection of β-thalasmia prenatal diagnosis of little value, and cord blood capillary electrophoresis and β-hemoglobin gene and detection of anemia is to have a good complementary .
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