OP0099Modular Repertoire Analysis Identifies Compl

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clap your hands>每况愈下rabbit是什么意思OP0099Modular Repertoire Analysis Identifies Complex Coordinated Type I- Type II Transcriptional Signatures in Adult SLE Patients 期刊名称: Annals of the Rheumatic Dias
the kite runner作者: Chiche, L.,Jourde-Chiche, N.,Whalen, E.,Dang, K.,Presnell, S.,Gersuk,
V.,Nguyen, Q.-A.,Anguiano, E.,Quinn, C.,Dussol, B.,Burtey, S.,Berland, Y.,Bardin, N.,Schleinitz, N.,Kaplanski, G.,Durand, J.-M.,Harle, J.-R.,Pascual, V.,Chaussabel, D.英国巨石阵石料来源之谜被揭开
年份: 2014年new divide歌词
get through期号: 第Suppl 2期
摘要:Background A pivotal role for Type I interferon (IFN) in SLE is supported by gene expression studies that identified the so-called type I IFN signature (IS). Objectives The aim of this study was to improve characterization of the blood-IFN signature in adult SLE patients. Methods Concutive SLE patients fulfilling the ACR criteria were enrolled and followed-up prospectively. Microarray data were generated using Illumina beadchips. A modular transcriptional repertoire was employed as a framework romario
naked news koreafor the analysis. Results Our repertoire of 260 modules, which consist of co-clustered gene ts, included 3 IFN-annotated modules (M1.2, M3.4 and M5.12) that were strongly up-regulated in SLE patients. At the individual level, a modular IS (ie, over-expression of at least 1 of the 3 IFN modules) was obrved in 54/62 (87%) of patients or
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