过错的意思Intra-individual variability in clopidogrel responsiveness in coronary artery dia patients
under long term therapy.
期刊名称: Platelets
nomi
作者: Arméro, Sébastien,Camoin Jau, Laurence, A?t Mokhtar, Omar,Mancini,
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Julien,Burignat-Bonello, Caroline,Tahirou, Iliassou,Arques, Stéphane, Dignat-
George, Fran?oi,Paganelli, Franck,Bonello, Laurent
warned年份: 2010年
work out
jdz>vsat期号: 第7期
关键词: Clopidogrel;coronary artery dia;percutaneous coronary
intervention;VASP index宣布英文
治疗青春痘方法
摘要:Clopidogrel responsiveness (CR) following a loading do (LD) predicts thrombotic events after percutaneous coronary interventions (PCI). Some of the mechanisms involved in large inter-individual variability in CR may be varied. We therefore postulated that there may be an intra-individual variability in CR. Two hundred and one patients receiving long-term therapy with aspirin and clopidogrel after drug-eluting stents PCI were prospectively included in this monocentre study along with any patient re-admitted within 12 months post-PCI. Platelet reactivity (PR) inhibition was assd by the vasodilator phosphoprotein (VASP) index following a 600 mg loading do of clopidogrel on each admission to determine CR (VASP 1 during the first admission and VASP 2 during re-admission). DeltaVASP = VASP 2 –VASP 1 was ud to
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