分子复习题
Section A
Differentiation: P3.
Complex macromolecules: P9
判断题：
1. Polysaccharides are polymers of simple sugars covalently linked by glycosidic bonds. T
2. Differential centrifugation is according to the value of dimentation coefficients. T
3. In mitochondria the light-dependent assimilation of CO2 and water to form carbohydrates and oxygen. F
4. Oxidation of nutrients to generate energy in the form of adenosine 5’-triphosphate (ATP) occurs in mitochondria. T
5. Differential centrifugation is ud to parate organelles of similar densities. F
6. In equilibrium centrifugation, the density gradient extends to a density higher than that of one or more components of the mixture so that the components come to equilibrium at a point equal to their own density and stop moving. T
选择题：
1. Which of the following is an example of a nuleoprotein?
秘社第二季A．keratin B．chromatin C．histone D．proteoglycan
填空题：
1. Like all other cellular process, differentiation if controlled by genes .
2. The rough endoplasmic reticulum has attached ribosomes engaged in the synthesis of membrane-targeted and creted proteins .
3. Proteins are polymers of amino acids , and the nucleic acids DNA and RNA are polymers of nucleotides .
4. Associations of nucleic acid and protein are known as nucleoproteins .
Section C
Hybridization: The renaturation of complementary quences between different nucleic acid molecules. Nucleosides: P33
noveltyHypochromicity：P44
扶手椅判断题：
1. Denaturation of double stranded DNA involves hydrolysis of the DNA backbone. F
2. The double helices of DNA and RNA condary structure are stabilized by the hydrogen bonding between ba pairs. F
3. In strong acid and at elevated temperatures, nucleic acids are hydrolyzed completely to their constituents. T
英语人物介绍4. Incread temperature can bring about the denaturation of DNA and RNA. T
选择题：
1. Which of the following correctly describes B-DNA? ( )
A. a right-handed antiparallel double helix with 10 bp/turn
B. a right-handed antiparallel double helix with 12 bp/turn
C. a left-handed antiparallel double helix with 10 bp/turn
D. a left-handed antiparallel double helix with 12 bp/turn
2. Denaturation of double stranded DNA involves ( )
beautiful mindA. breakage into short double-stranded fragment
B. paration into single strands
C. hydrolysis of the DNA backbone
D. cleavage of the bas from the sugar-phosphate backbone
3. The quence 5’-AGTCTGACT-3’ in DNA is equivalent to which quence in RNA?
A. 5’-AGUCUGACU-3’
B. 5’-UGTCTGUTC-3’
4. Which has the highest absorption per unit mass at a wavelength of 260 nm?
A. double-stranded DNA
B. mononucleotides
C. RNA
滚动体D. protein
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填空题：
1. The A260/A280 ratio of a double-stranded DNA sample can be ud to asss its purity. For pure DNA, the value is 1.8. Above this value suggest RNA contamination and below this value suggest protein contamination.
2. Ba+sugar+phosphate= nucleotide .
3. Ba+sugar = nucleoside .
4. In DNA, there are four heterocyclic bas: A and G are purines; C and T are pyrimidines.
5. The absorbance of isolated nucleotides is greater than that of RNA and single stranded DNA.
6. In nucleosides, the bond between the bas and the sugars is the glycosylic bond.
美国法学院校专业申请要求和流程Section D
DNa I hypernsitivity: Active regions of chromatin or regions where the 30 nm fiber is interrupted by the binding of a specific protein to the DNA or by ongoing transcription are characterized by hypernsitivity to deoxyribonuclea Ⅰ.
判断题：
1. All histone proteins have a large positive charge. T
2. A large proportion of the DNA in eukaryotic cells does not code for protein. T
选择题：
1. Which of the following is common to li and eukaryotic chromosomes?
A. the DNA is circular
B. the DNA is packaged into nucleosomes
C. the DNA is contained in the nucleus
D. the DNA is negatively supercoiled
2. In what region of the interpha chromosome does transcription take place?
A. the telomere
B. the centromere
C. euchromatin
D. heterochromatin
3. A complex of 166 bp of DNA with the histone octamer plus histone H1 is known as a ( )
A. nucleosome core
无锡翻译B. solenoid
C. 30 nm fiber
D. chromatosome
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4. Which statement about CpG islands and methylation is not true?
A. CpG islands are particularly resistant to DNa I
B. CpG methylation is responsible for the mutation of CpG to TpG in eukaryotes
