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Title: Diagnostic analysis of acute non-lymphocytic leukemia with breast infiltration as the first symptom: a report of 6 cas
Article Type: Regular Article
Keywords: Breast; Myeloid sarcoma; Acute nonlymphocytic leukemia; Diagnosis and therapy Corresponding Author: Dr. Min Ren,
Corresponding Author's Institution: of Breast Surgery, The First Affiliated Hospital of Anhui Medical University
First Author: Min Ren
Order of Authors: Min Ren; Benzhong Wang, MS; Jin Wang, MS; Jingjie Zhang, MS; Jing Pei, MS; Xiaojun Xu, MS; Yunwen Yan, MS; Jun Xu, MS; Ying Chen, MS
Cover Letter
Dear editors,
We would like to contribute the manuscript with the following title and authors for
publication in Biochemical and Biophysical Rearch Communications.
Title:Diagnostic analysis of acute non-lymphocytic leukemia with breast infiltration
as the first symptom: a report of 6 cas
Authors: Min Ren*, Benzhong Wang, Jin Wang, Jingjie Zhang, Jing Pei, Xiaojun Xu,
Yunwen Yan, Jun Xu, Ying Chen
Cas of acute non-lymphocytic leukemia (ANLL) that prent with breast infiltration
所以然
as the first symptom are rare dias and easy to misdiagnosis. We systematically
reviewed literature and analyzed the diagnosis and treatment of six cas who were
clean code
admitted for the treatment of a breast mass, but were eventually diagnod as ANLL
(M2a phenotype) with breast infiltration. In conclusion, to avoid this dia
misdiagnosis and detours, appropriate examinations should be performed to allow for
early detection. Moreover, this should be combined with bone marrow cytology and
男生瓜子脸发型pathology examinations to diagno and treat this type of leukemia at the earliest
stage possible.
We declare that submitted manuscript does not contain previously published material,
and are not under consideration for publication elwhere. Each author has made an
important scientific contribution to the study and is thoroughly familiar with the
primary data. All authors listed have read the complete manuscript and have approved
submission of the paper. The manuscript is truthful original work without fabrication,
fraud or plagiarism. All authors declare that there are no conflicts of interest.伦敦奥运会吉祥物
We would be happy if the manuscript will be evaluated by your Editorial Board
members for publication in the Biochemical and Biophysical Rearch
Communications.
Thank you for your kind cooperation with this matter in advance.
With best regards,
Sincerely yours,
Min Ren
Department of Breast Surgery,
The First Affiliated Hospital of Anhui Medical University, Hefei 30022, China.
Tel: +86-138********
Fax: +86-5512922043
Email:
*Highlights (for review)
解释英文Diagnostic analysis of acute non-lymphocytic leukemia with breast infiltration as
the first symptom: a report of 6 cas
Min Ren*, Benzhong Wang, Jin Wang, Jingjie Zhang, Jing Pei, Xiaojun Xu, Yunwen Yan, Jun
Xu, Ying Chen
Department of Breast Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei
30022, China.
This dia is very rare and easily misdiagnod.
We conducted a systematic diagnosis and analysis rather than direct treatment.
自作主张
To take timely and effective treatment after diagnosis.
No obvious recurrence was detected during the follow-up period.
英语绘本We propo a more comprehensive diagnostic and treatment strategies.
*Manuscript
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Diagnostic analysis of acute non-lymphocytic leukemia with breast infiltration as
the first symptom: a report of 6 cas
Min Ren*, Benzhong Wang, Jin Wang, Jingjie Zhang, Jing Pei, Xiaojun Xu, Yunwen Yan, Jun
Xu, Ying Chen
Department of Breast Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei
30022, China.
Email Address:
Min Ren (); Benzhong Wang ();
Jin Wang (); Jingjie Zhang (); Jing Pei
(); Xiaojun Xu (); Yunwen Yan
(); Jun Xu (); Ying Chen
()
*Corresponding Author
Min Ren
Department of Breast Surgery,
The First Affiliated Hospital of Anhui Medical University,
Hefei 30022, China.
Tel: +86-138********
Fax:+86-5512923863
Email:
Abbreviations
acute non-lymphocytic leukemia: ANLL
momy
granulocytic sarcoma: GS
daunorubicin + Ara-C : DA
emission CT : ECT
myeloperoxida : MPO
non-Hodgkin's lymphoma : NHL
chronic myelogenous leukemia : CML
myelodysplastic syndrome : MDS
acute myelogenous leukemia : AML
Abstract
母亲的故事
Cas of acute non-lymphocytic leukemia (ANLL) that prent with breast infiltration as the first symptom are rare dias and easy to misdiagnosis. We systematically reviewed literature and analyzed the diagnosis and treatment of six cas who were admitted for the treatment of a breast mass, but were eventually diagnod as ANLL (M2a phenotype) with breast infiltration. Then they were transferred to the hematology department for standardized chemotherapy. Their peripheral blood cells gradually recovered to normal levels and symptoms disappeared. One patient, who also suffered from kidney dia, was also healed. No obvious recurrence was detected during the follow-up period, which lasted between 14 and 38 months. In conclusion, to avoid this dia misdiagnosis and detours, appropriate examinations should be performed to allow for early detection. Moreover, this should be combined with bone marrow cytology and pathology examinations to diagno and treat this type of leukemia at the earliest stage possible.
Keywords: Breast; Myeloid sarcoma; Acute nonlymphocytic leukemia; Diagnosis and therapy
