Noisy silence
fight是什么意思
surrender期刊名称： Epigenetics
作者： Bierhoff, Holger,Postepska-Igielska, Anna,Grummt, Ingrid
暴利税年份： 2014年
英语毕业论文范文
就手期号： 第1期
关键词： non-coding RNA;heterochromatin;repetitive
distance什么意思elements;rDNA;centromeres;telomeres;retrotransposons
eol摘要：A significant fraction of eukaryotic genomes compris repetitive quences, including rRNA genes, centromeres, telomeres, and retrotransposons. Repetitive elements are hotspots for recombination and reprent a rious challenge for genome integrity. Maintaining the repeated elements in a compact heterochromatic structure suppress recombination and unwanted mutagenic t
ransposition, and is therefore indispensable for genomic stability. Paradoxically, repetitive elements are not transcriptionally inert, but produce RNA that has important functions in regulating and reinforcing the heterochromatic state. Here, we review the role of non-coding RNA (ncRNA) in recruiting chromatin-modifying enzymes to repetitive genomic loci to establish a repressive chromatin structure that safeguards chromosome integrity and genome stability.
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2012英语六级真题>多伦多大学世界排名内容由中国教育图书进出口有限公司引进
