RpoS-regulated SEN1538 gene promotes resistance to stress and influences Salmonella enterica rovar
enteritidis virulence
期刊名称: Virulenceanthony hamilton
作者: Aryashree Arunima,Sunil Kumar Swain,Shilpa Ray,Birendra Kumar
Prusty,Mrutyunjay Suar
年份: 2020年jaci velasquez
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compendium>wrapup关键词: virulence
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改善记忆摘要:Salmonella enterica rovar Enteritidis (S. Enteritidis; wild type (WT)) is a major cau of foodborne illness globally. The ability of this pathogen to survive stress inside and outside the host, such as encountering antimicrobial peptides and heat stress, determines the efficiency of enteric infecti
on. The stressors concertedly trigger virulence factors encoded on Salmonella pathogenicity islands (SPIs). Although RpoS is a well-known central transcriptional stress and virulence regulator, functional information regarding the genes of the regulon is currently limited. Here, we identified SEN1538 as a conrved RpoS-regulated gene
belonging to the KGG protein superfamily. We further assd its role in pathogenic stress respons and virulence. When SEN1538 was deleted (Δ1538), the pathogen showed reduced 四六级将提供电子成绩报告单>weir
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