HIV-INTEGRASE INHIBITORS, PHARMACEUTICAL COMPOSIT

更新时间:2023-05-27 03:04:42 阅读: 评论:0

专利名称:HIV-INTEGRASE INHIBITORS,
ホタルノヒカリPHARMACEUTICAL COMPOSITIONS, AND
METHODS FOR THEIR USE
发明人:KUKI, Atsuo,LI, Xinqiang,PLEWE, Michael, Bruno,WANG, Hai,ZHANG, Junhu
申请号:IB2004000259
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申请日:20040123
公开号:WO04/067531P1
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公开日:
exiled>突出
20040812
专利内容由知识产权出版社提供丹顶鹤英文
摘要:Beta-carboline hydroxamic acid compounds reprented by formula (I) and formula (lb) are described, wherein: R1, R2, R3, R4, R5, and R6 are independently lected from hydrogen, halogen, C1_C6 alkyl, aikoxy C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -ORc, -NO2, and -N(Rc)2, each Rc is Independently lected from hydrogen, C1-C6 alkyl,
C2-C6 alkenyl, and C2-Ca alkynyl; R7 Is C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl, all of which are optionally substituted by one or more substituents independently lected from halogen, C1-C6 alkyl, C2-C6 alkenyl; C2-C6 alkynyl, aryl, cycloalkyl, heterocycioalkyl, and heteroaryl, wherein said aryl, cydoalkyi, and heterocycloalkyl are optionally substituted with one or more substituents independently lected from halogen, C1-C6 alkyl, C2-C6 alkenyl, and C2-C6 alkynyl; R8 and R9 are independently lected from hydrogen, C1-C6 alkyl, C2-C6 alkenyl, and C2-C6 aikynyl, wherein said alkyl, alkenyl, and alkynyl are optionally substituted with one or more substituents independently lected from halogen, aryl, cycloalkyl, heterocycloalkyl, and heteroaryl group, wherein said aryl, cyc
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loalkyl, and heterocycloalkyl are optionally substituted with one or more substituents
independently lected from halogen, C1-C6 alkyl, C2-C6 alkenyl, and C2-C6 alkynyl. The beta-carboline hydroxamic acid compounds and compositions containing tho compounds may be ud to inhibit or modulate the activity of HIV integra enzyme and to treat HIV integra-mediated dias and conditions.
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申请人:KUKI, Atsuo,LI, Xinqiang,PLEWE, Michael, Bruno,WANG, Hai,ZHANG, Junhu 地址:235 East 42nd New York, NY 10017 US,Agouron Pharmaceuticals, Inc. A Pfizer Company 10777 Science Center Drive San Diego, CA 92121 US,Agouron Pharmaceuticals Inc. A Pfizer Company 10777 Science Center Drive San Diego, CA 92121 US,Agouron Pharmaceuticals, Inc. A Pfizer Company 10777 Science Center Drive San Diego, CA 92121 US,Agouron Pharmaceuticals, Inc. A Pfizer Company 10777 Science Center Drive San Diego, CA 92121 US,Agouron Pharmaceuticals, Inc. A Pfizer Company 10777 Science Center Drice San Diego, CA 92121 US星期四英语怎么说
人教版初一英语下册国籍:US,US,US,US,US,US
代理机构:LUMB, J., Trevor
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