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Product Data Sheet
Product Name:eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]美食男孩冒险记
Cat. No.:GP10018 Chemical Properties
Cas No.N/A
Chemical
Name
N/A
软实力培训Canonical SMILES NC(CC(C)C)C(NC(CCC(O)=O)C(NC(CC(O)=O)C(NCC(N(CCC1)C1C(NC(CCCCN)
ebay是什么意思C(NC(CC2=CC=CC=C2)C (NC(CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=Oltaly
Formula C43H67N9O13M.Wt918.04 Solubility≥91.8mg/mL in DMSO Storage Store at -20°C
General tips For obtaining a higher solubility , plea warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for veral months.
Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request.
Structurerecycler
Background
Sequence: LEU-GLU-ASP-GLY-PRO-LYS-PHE-LEU
Product Data Sheet
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expresd in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expresd in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, reprent different pudogenes1.
拼写的英文There are two forms of eEF1A in eukaryotes, eEF1A1 and eEF1A2, both of which posss the same role in protein synthesis2. eEF1A2 was reported to be exclusively expresd in brain, heart, and skeletal muscle, whereas eEF1A1 is well known to be ubiquitously expresd3.
kingbosstetraploid cells produced by impaired chromosomal condensation are eliminated by a novel type of cell death
different from caspa-dependent apoptosis. The cell death was associated with downregulation of eukaryotic translation elongation factor-1 a 1 (eEF1A1/EF-1a) expression in conjunction with accumulation of its mRNA in processing bodies (P bodies). Importantly, expression of exogenous eEF1A1 was shown to inhibit the caspa-independent cell death, and a similar cell death was obrved after inducing the expression of short hairpin RNA speci?c for eEF1A12.本科学位证查询>粗心的什么
References:
1. "Entrez Gene: EEF1A1 eukaryotic translation elongation factor 1 alpha 1"
2. Kahns S, LundA, Kristenn P, Knudn CR, ClarkBF, Cavallius J et al. The elongationfactor 1 A-2 isoform from rabbit: cloning of the cDNA and characterization of the protein. Nucleic Acids Res 1998; 26: 1884-1890
3. Lee S, Francoeur AM, Liu S, Wang E. Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family. J Biol Chem 1992; 267: 24064-24068.
4. Y Kobayashi and S Yonehara. Cell Death and Differentiation (2009) 16, 139-150
