专利名称：Clonal expansion of T cells of unknown
tebspecificity and identification of ligand
recognized by the clonally expanded T cells 发明人：Sho Matsushita,Toshihiro Nakashima
申请号：US09962445
tempo丶topteam申请日：20010926
公开号：US20020192705A1
公开日：
chinabig
2020年9月四级成绩查询时间
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20021219
专利内容由知识产权出版社提供绿茶英语
摘要：A process for clonally expanding T cells of unknown specificity is provided which compris co-culturing said T cells of unknown specificity with combinatorial randomized peptide library, Xn, an interleukin, and MHC class II antigen-expressing cells with DNA synthesis being suspended, said cells being derived from the individual where said T cells are obtained, and optionally in the prence of anti-CD29 antibody having an agonist activity. A process for identifying a peptide ligand recognized by said T cell clone of unknown specificity is also provided.
申请人：MATSUSHITA SHO,NAKASHIMA TOSHIHIRO
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