Rheumatoid arthritis–associated DNA methylation sites in peripheral blood mononuclear cells
网页编程培训期刊名称： Annals of the Rheumatic Dias
音标mp3>绘本在线阅读作者： Zhu, Hong,Wu, Long-Fei,Mo, Xing-Bo,Lu, Xin,Tang, Hui,Zhu, Xiao-Wei,Xia, Wei,Guo, Yu-Fan,Wang, Ming-Jun,Zeng, Ke-Qin,Wu, Jian,Qiu, Ying-Hua,Lin,韩语语音
Xiang,Zhang, Yong-Hong,Liu, Yao-Zhong,Yi, Neng-Jun,Deng, Fei-Yan,Lei, Shu-
Feng
experimenting
年份： 2018年
saving private ryan关键词： rheumatoid arthritis;t cells;autoimmune dias
英语四级准考证号忘了
摘要：Objectives To identify novel DNA methylation sites significant for rheumatoid arthritis (RA) and comprehensively understand their underlying pathological mechanism. Methods We performed (1) genome-wide DNA methylation and mRNA expression profiling in peripheral blood mononuclear cells fr
hearts
om RA patients and health controls; (2) correlation analysis and causal inference tests for DNA methylation and mRNA expression data; (3) differential methylation genes regulatory network construction; (4) validation tests of 10 differential methylation positions (DMPs) of interest and corresponding gene expressions; (5) correlation between PARP9 methylation and its mRNA expression level in Jurkat cells and T cells from patients with RA; (6) testing the pathological functions of PARP9 in Jurkat cells. Results A total of 1046 DNA methylation
peoples
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>英语课后反思
