孕中期检测血清AFP\Free-β-hCG和inhibin-A产前筛查的临床价值

更新时间:2023-07-19 09:09:18 阅读: 评论:0

rafalechandra孕中期检测血清AFP\Free-β-hCG和inhibin-A产前筛查的临床价值gentleman
目的 探讨孕中期血清标记物甲胎蛋白(AFP)、游离β-人绒毛膜促性腺激素(Free-β-hCG)和抑制素A(inhibin-A)在产前筛查的实用价值。方法 对3728例孕14~20周的孕妇分别采用化学发光法和酶联免疫方法检测血清AFP、Free-β-hCG和inhibin-A浓度,通过计算机软件计算危险系数,对高风险率孕妇进行遗传咨询,在知情同意的情况下进行羊水细胞染色体的产前检查。结果 在3728例孕妇中筛查出唐氏综合征、18-三体及神经管缺损高危孕妇163例,占筛查总数的4.37%。91例进一步确诊,共检出先天缺陷7例,检出率为7.69%。结论 孕中期血清中AFP、Free-β-hCG和inhibin-A用于产前筛查能早期发现和诊断胎儿先天缺陷,对降低其出生率是有效的,可以应用于临床大范围人群的产前筛查。
标签: AFP; Free-β-hCG; inhibin-A; 产前筛查do you think so
The clinical effect of rum AFP、Free-β-hCG and inhibin-A on prenatal screening in mid-pregnancy XIA Yi,XU Jing-xuan,TANG Ya-juan, HUANG Hong-qin.The Second Hospital of Danyang,Jiangsu 212300,China
英语四级满分多少>yousheng
中秋节英语翻译
【Abstract】 Objective To investigate the clinical practical effect of rum AFP、Free-β-hCG and inhibin-A on prenatal screening in mid-pregnancy.Methods Chemoluminescence and ELISA were applied to measuring the rum levels of AFP, Free-β-hCG and inhibin-A in 3728 cas of pregnant women at about 14th-20th weeks’ gestation and the risk coefficient was calculated with professional computer software, hereditary consultation was provided for the high risk pregnant women by measuring the high risk rate with special software, amniocentesis was done with their agreement.Results In 3728 cas of pregnant women,163 cas(4.37%) were high risk for Down’s syndrome, trisomy 18 and NTD. There were 7 cas with congenital defects in 91 cas, total positive rate was 7.69%.Conclusion It is operative to decrea birth rate of the fetus with congenital defects by measuring rum AFP、Free-β-hCG and inhibin-A in mid-pregnancy, which can early discover diagno the fetus with congenital defects. And, the strategy may be ud on clinical prenatal screening in extensiveness crowd.
顺德碧桂园学校>foody

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标签:筛查   血清   孕妇   缺陷
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